Research Article
Cytotoxic Activities against Breast Cancer Cells of Local Justicia gendarussa Crude Extracts
Table 2
Percentage viability of MDA-MB-231 cells in leaf extracts from five different locations.
| Concentration (μg/mL) | 7.81 | 15.63 | 31.25 | 62.5 | 125 | 250 | 500 | 1000 |
| Leaf extract from Mersing |
60.25 ± 0.06 | 54.35 ± 0.05 | 55.95 ± 0.08 | 33.91 ± 0.07 | 24.08 ± 0.02 | 23.78 ± 0.02 | 17.60 ± 0.03 | 29.85 ± 0.08 |
| Leaf extract from Muar | 79.26 ± 0.07 | 72.89 ± 0.07 | 71.35 ± 0.08 | 70.34 ± 0.07 | 63.49 ± 0.09 | 54.58 ± 0.04 | 8.29 ± 0.01 | 11.54 ± 0.02 |
| Leaf extract from Skudai | 67.41 ± 0.03 | 64.76 ± 0.01 | 55.77 ± 0.03 | 50.44 ± 0.03 | 49.61 ± 0.01 | 47.07 ± 0.04 | 8.42 ± 0.01 | 11.65 ± 0.01 |
| Leaf extract from Batu Pahat | 82.67 ± 0.07 | 78.96 ± 0.02 | 77.20 ± 0.02 | 60.89 ± 0.01 | 58.22 ± 0.01 | 50.59 ± 0.01 | 11.40 ± 0.01 | 10.28 ± 0.01 |
| Leaf extract from Pulai | 74.61 ± 0.08 | 73.06 ± 0.07 | 69.24 ± 0.09 | 66.06 ± 0.10 | 65.44 ± 0.10 | 60.58 ± 0.07 | 53.23 ± 0.03 | 16.71 ± 0.02 |
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Values are mean ± STDEV for 3 replicates < 0.05, < 0.01, and < 0.001 compared to control (untreated cell).
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