Apocynum Tablet Protects against Cardiac Hypertrophy via Inhibiting AKT and ERK1/2 Phosphorylation after Pressure Overload

Figure 3

Histological sections of the left ventricular (LV) wall (Groups: NS-SHAM, NS-TAC, AT-SHAN and AT-TAC mice). (a) The LV cross sections of the four groups stained with H&E (×400 magnification, Scale bar, 20 μm) and Sirius red (red staining, ×40 magnifications, Scale bar, 200 μm). (b) Mean cross-sectional area of cardiomyocytes and (c) the fraction of fibrotic area. ^∗𝑃<0.05, ^∗∗𝑃<0.01, and ^∗∗∗𝑃<0.001, comparison among the groups.

(a) HE/Sirus staining

(b)

(c)