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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 780385, 5 pages
http://dx.doi.org/10.1155/2014/780385
Research Article

Crotonis Fructus and Its Constituent, Croton Oil, Stimulate Lipolysis in OP9 Adipocytes

1Center for Metabolic Function Regulation, Wonkwang University School of Medicine, No. 460 Iksan-Daero, Iksan, Jeonbuk 570-749, Republic of Korea
2BK21 Plus Program and Department of Smart Life-Care Convergence, Graduate School, Wonkwang University, No. 460 Iksan-Daero, Iksan, Jeonbuk 570-749, Republic of Korea
3Department of Oral Biochemistry, Wonkwang University School of Dentistry, No. 460 Iksan-Daero, Iksan, Jeonbuk 570-749, Republic of Korea
4Institute of Customized Physical Therapy, No. 217 Wallgye-ro, Gwangju Metropolitan City 506-303, Republic of Korea
5Department of Korean Physiology, Wonkwang University School of Korean Medicine, No. 460 Iksan-Daero, Iksan, Jeonbuk 570-749, Republic of Korea
6Department of Internal Medicine, Wonkwang University School of Medicine, No. 460 Iksan-Daero, Iksan, Jeonbuk 570-749, Republic of Korea
7Department of Herbology, Wonkwang University School of Korean Medicine, No. 460 Iksan-Daero, Iksan, Jeonbuk 570-749, Republic of Korea
8Department of Sports Industry & Welfare, Wonkwang University School of Natural Science, No. 460 Iksan-Daero, Iksan, Jeonbuk 570-749, Republic of Korea

Received 4 August 2014; Accepted 23 October 2014; Published 11 November 2014

Academic Editor: Waris Qidwai

Copyright © 2014 Mi-Seong Kim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J.-C. Tsai, S. Tsai, and W.-C. Chang, “Effect of ethanol extracts of three Chinese medicinal plants with anti-diarrheal properties on ion transport of the rat intestinal epithelia,” Journal of Pharmacological Sciences, vol. 94, no. 1, pp. 60–66, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. X. Wang, M. Lan, H.-P. Wu et al., “Direct effect of croton oil on intestinal epithelial cells and colonic smooth muscle cells,” World Journal of Gastroenterology, vol. 8, no. 1, pp. 103–107, 2002. View at Google Scholar · View at Scopus
  3. J. Hu, W.-Y. Gao, L. Ma, S.-L. Man, L.-Q. Huang, and C.-X. Liu, “Activation of M3 muscarinic receptor and Ca2+ influx by crude fraction from Crotonis Fructus in isolated rabbit jejunum,” Journal of Ethnopharmacology, vol. 139, no. 1, pp. 136–141, 2012. View at Publisher · View at Google Scholar · View at Scopus
  4. M. Lan, P. Wan, Z.-Y. Wang, and X.-L. Huang, “GC-MS analysis of chemical components in seeds oil from Croton tiglium,” Journal of Chinese Medicinal Materials, vol. 35, no. 7, pp. 1105–1108, 2012. View at Google Scholar · View at Scopus
  5. X. Wang, F. Zhang, Z. Liu et al., “Effects of essential oil from Croton tiglium L. on intestinal transit in mice,” Journal of Ethnopharmacology, vol. 117, no. 1, pp. 102–107, 2008. View at Publisher · View at Google Scholar · View at Scopus
  6. K. Jaworski, E. Sarkadi-Nagy, R. E. Duncan, M. Ahmadian, and H. S. Sul, “Regulation of triglyceride metabolism. IV. Hormonal regulation of lipolysis in adipose tissue,” American Journal of Physiology: Gastrointestinal and Liver Physiology, vol. 293, no. 1, pp. G1–G4, 2007. View at Publisher · View at Google Scholar · View at Scopus
  7. R. E. Duncan, M. Ahmadian, K. Jaworski, E. Sarkadi-Nagy, and H. S. Sul, “Regulation of lipolysis in adipocytes,” Annual Review of Nutrition, vol. 27, pp. 79–101, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. M. J. Watt and L. L. Spriet, “Triacylglycerol lipases and metabolic control: implications for health and disease,” American Journal of Physiology—Endocrinology and Metabolism, vol. 299, no. 2, pp. E162–E168, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Lass, R. Zimmermann, M. Oberer, and R. Zechner, “Lipolysis—a highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores,” Progress in Lipid Research, vol. 50, no. 1, pp. 14–27, 2011. View at Publisher · View at Google Scholar · View at Scopus
  10. C. Holm, “Molecular mechanisms regulating hormone-sensitive lipase and lipolysis,” Biochemical Society Transactions, vol. 31, no. 6, pp. 1120–1124, 2003. View at Publisher · View at Google Scholar · View at Scopus
  11. N. E. Wolins, B. K. Quaynor, J. R. Skinner et al., “OP9 mouse stromal cells rapidly differentiate into adipocytes: characterization of a useful new model of adipogenesis,” Journal of Lipid Research, vol. 47, no. 2, pp. 450–460, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. H.-R. Kim, J.-M. Kim, M.-S. Kim et al., “Inhibitory effects of Pericarpium zanthoxyli extract on adipocyte differentiation,” International Journal of Molecular Medicine, vol. 33, no. 5, pp. 1140–1146, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. M. M. Bradford, “A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein dye binding,” Analytical Biochemistry, vol. 72, no. 1-2, pp. 248–254, 1976. View at Publisher · View at Google Scholar · View at Scopus
  14. J. H. Kim, S. J. Lee, Y. B. Han, J. J. Moon, and J. B. Kim, “Isolation of isoguanosine from Croton tiglium and its antitumor activity,” Archives of Pharmacal Research, vol. 17, no. 2, pp. 115–118, 1994. View at Publisher · View at Google Scholar · View at Scopus
  15. M. J. Watt, A. G. Holmes, S. K. Pinnamaneni et al., “Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue,” American Journal of Physiology: Endocrinology and Metabolism, vol. 290, no. 3, pp. E500–E509, 2006. View at Publisher · View at Google Scholar
  16. A. S. Greenberg, W.-J. Shen, K. Muliro et al., “Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway,” The Journal of Biological Chemistry, vol. 276, no. 48, pp. 45456–45461, 2001. View at Publisher · View at Google Scholar · View at Scopus
  17. N. M. Anthony, M. P. Gaidhu, and R. B. Ceddia, “Regulation of visceral and subcutaneous adipocyte lipolysis by acute AICAR-induced AMPK activation,” Obesity, vol. 17, no. 7, pp. 1312–1317, 2009. View at Publisher · View at Google Scholar · View at Scopus