Evidence-Based Complementary and Alternative Medicine / 2014 / Article / Fig 3

Research Article

Effect of Estragole on Leukocyte Behavior and Phagocytic Activity of Macrophages

Figure 3

EST inhibited in vivo leukocyte migration in rats. The animals were orally treated with EST (250, 500, or 750 mg/kg) and indomethacin (5.0 mg/kg) 30 minutes before the injection of carrageenan (100 μg/scrotum). (a) Number of leukocytes rolling, (b) number of leukocytes adherent during 10-minute periods after 2 h, and (c) leukocytes migrate after 4 h of inflammatory stimulus. Values represent mean ± SEM ( animals/group) and are representative of three independent experiments. versus vehicle; versus carrageenan-injected group (one-way ANOVA, Tukey’s test).