Table of Contents Author Guidelines Submit a Manuscript
Evidence-Based Complementary and Alternative Medicine
Volume 2014 (2014), Article ID 796518, 7 pages
http://dx.doi.org/10.1155/2014/796518
Research Article

Effects of Inhalation of Essential Oil of Citrus aurantium L. var. amara on Menopausal Symptoms, Stress, and Estrogen in Postmenopausal Women: A Randomized Controlled Trial

Department of Basic Nursing Science, School of Nursing, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 136-701, Republic of Korea

Received 29 April 2014; Revised 20 May 2014; Accepted 30 May 2014; Published 12 June 2014

Academic Editor: Ping Liu

Copyright © 2014 Seo Yeon Choi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. C. Fantasia and M. A. Sutherland, “Hormone therapy for the management of menopause symptoms,” Journal of Obstetric, Gynecologic, & Neonatal Nursing, vol. 43, no. 2, pp. 226–235, 2014. View at Google Scholar
  2. N. E. Avis, A. Colvin, J. T. Bromberger et al., “Change in health-related quality of life over the menopausal transition in a multiethnic cohort of middle-aged women: study of Women’s Health Across the Nation,” Menopause, vol. 16, no. 5, pp. 860–869, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. W. G. Rossmanith and W. Ruebberdt, “What causes hot flushes? the neuroendocrine origin of vasomotor symptoms in the menopause,” Gynecological Endocrinology, vol. 25, no. 5, pp. 303–314, 2009. View at Publisher · View at Google Scholar · View at Scopus
  4. O. Ortmann and C. Lattrich, “The treatment of climacteric symptoms,” Deutsches Arzteblatt, vol. 109, no. 17, pp. 316–324, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. N. F. Col, G. Weber, A. Stiggelbout, J. Chuo, R. D'Agostino, and P. Corso, “Short-term menopausal hormone therapy for symptom relief: an updated decision model,” Archives of Internal Medicine, vol. 164, no. 15, pp. 1634–1640, 2004. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Daley, H. Stokes-Lampard, and C. Macarthur, “Exercise for vasomotor menopausal symptoms,” Cochrane Database of Systematic Reviews, no. 5, Article ID CD006108, 2011. View at Google Scholar · View at Scopus
  7. G. M. Dickson, “Menopause management: how you can do better,” Journal of Family Practice, vol. 61, no. 3, pp. 138–145, 2012. View at Google Scholar · View at Scopus
  8. F. Borrelli and E. Ernst, “Alternative and complementary therapies for the menopause,” Maturitas, vol. 66, no. 4, pp. 333–343, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. C. A. R. A. Costa, T. C. Cury, B. O. Cassettari, R. K. Takahira, J. C. Flório, and M. Costa, “Citrus aurantium L. essential oil exhibits anxiolytic-like activity mediated by 5-HT1A-receptors and reduces cholesterol after repeated oral treatment,” BMC Complementary and Alternative Medicine, vol. 13, article 42, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. L.-T. Yi, H.-L. Xu, J. Feng, X. Zhan, L.-P. Zhou, and C.-C. Cui, “Involvement of monoaminergic systems in the antidepressant-like effect of nobiletin,” Physiology and Behavior, vol. 102, no. 1, pp. 1–6, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. L. M. Lopes Campêlo, C. Gonçalves e Sá, A. A. C. de Almeida et al., “Sedative, anxiolytic and antidepressant activities of Citrus limon (Burn) essential oil in mice,” Pharmazie, vol. 66, no. 8, pp. 623–627, 2011. View at Publisher · View at Google Scholar · View at Scopus
  12. A. A. C. de Almeida, J. P. Costa, R. B. F. de Carvalho, D. P. de Sousa, and R. M. de Freitas, “Evaluation of acute toxicity of a natural compound (+)-limonene epoxide and its anxiolytic-like action,” Brain Research, vol. 1448, pp. 56–62, 2012. View at Publisher · View at Google Scholar · View at Scopus
  13. T. G. do Vale, E. C. Furtado, J. G. Santos Jr., and G. S. B. Viana, “Central effects of citral, myrcene and limonene, constituents of essential oil chemotypes from Lippia alba (mill.) N.E. Brown,” Phytomedicine, vol. 9, no. 8, pp. 709–714, 2002. View at Publisher · View at Google Scholar · View at Scopus
  14. J. Shen, A. Niijima, M. Tanida, Y. Horii, K. Maeda, and K. Nagai, “Olfactory stimulation with scent of grapefruit oil affects autonomic nerves, lipolysis and appetite in rats,” Neuroscience Letters, vol. 380, no. 3, pp. 289–294, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. P. Kang, S. H. Suh, S. S. Min, and G. H. Seol, “The essential oil of Citrus bergamia Risso induces vasorelaxation of the mouse aorta by activating K + channels and inhibiting Ca 2+ influx,” Journal of Pharmacy and Pharmacology, vol. 65, no. 5, pp. 745–749, 2013. View at Publisher · View at Google Scholar · View at Scopus
  16. J. R. Hilditch, J. Lewis, A. Peter et al., “A menopause-specific quality of life questionnaire: development and psychometric properties,” Maturitas, vol. 24, no. 3, pp. 161–175, 1996. View at Publisher · View at Google Scholar · View at Scopus
  17. K. B. van Dole, R. F. Devellis, R. D. Brown, M. L. Jonsson Funk, B. N. Gaynes, and R. E. Williams, “Evaluation of the menopause-specific quality of life questionnaire: a factor-analytic approach,” Menopause, vol. 19, no. 2, pp. 211–215, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. O. Lee, J. Kim, H. Lee, and R. Choue, “Nutritional status, quality of diet and quality of life in postmenopausal women with mild climacteric symptoms based on food group intake patterns,” Korean Journal of Community, vol. 17, no. 1, pp. 69–80, 2012. View at Google Scholar
  19. M. E. Cline, J. Herman, E. R. Shaw, and R. D. Morton, “Standardization of the visual analogue scale,” Nursing Research, vol. 41, no. 6, pp. 378–380, 1992. View at Google Scholar · View at Scopus
  20. A. Bener, D. E. Rizk, H. Shaheen, R. Micallef, N. Osman, and E. V. Dunn, “Measurement-specific quality-of-life satisfaction during the menopause in an arabian gulf country,” Climacteric, vol. 3, no. 1, pp. 43–49, 2000. View at Google Scholar · View at Scopus
  21. R. Hardy and D. Kuh, “Change in psychological and vasomotor symptom reporting during the menopause,” Social Science and Medicine, vol. 55, no. 11, pp. 1975–1988, 2002. View at Publisher · View at Google Scholar · View at Scopus
  22. D. C. Deecher, “Physiology of thermoregulatory dysfunction and current approaches to the treatment of vasomotor symptoms,” Expert Opinion on Investigational Drugs, vol. 14, no. 4, pp. 435–448, 2005. View at Publisher · View at Google Scholar · View at Scopus
  23. C. J. Huang, H. E. Webb, M. C. Zourdos, and E. O. Acevedo, “Cardiovascular reactivity, stress, and physical activity,” Frontiers in Physiology, vol. 4, p. 314, 2013. View at Google Scholar
  24. K.-M. Chang and C.-W. Shen, “Aromatherapy benefits autonomic nervous system regulation for elementary school faculty in Taiwan,” Evidence-Based Complementary and Alternative Medicine, vol. 2011, Article ID 946537, 7 pages, 2011. View at Publisher · View at Google Scholar · View at Scopus
  25. F. Pellati, S. Benvenuti, M. Melegari, and F. Firenzuoli, “Determination of adrenergic agonists from extracts and herbal products of Citrus aurantium L. var. amara by LC,” Journal of Pharmaceutical and Biomedical Analysis, vol. 29, no. 6, pp. 1113–1119, 2002. View at Publisher · View at Google Scholar · View at Scopus