Free Radicals Scavenging Capacity, Antidiabetic and Antihypertensive Activities of Flavonoid-Rich Fractions from Leaves of Trichilia emetica and Opilia amentacea in an Animal Model of Type 2 Diabetes Mellitus

Table 2

Effect of flavonoid-rich fractions of Trichilia emetica (FT) and Opilia amentacea (FO) on blood glucose level for subacute study (multiday study).

	0 day	1 day	3 day	5 day	7 day
Normal control	84.60±1.10	85.68±1.00	84.33±2.10	84.57±1.00	84.53±1.52
Diabetic control	176.2±3.30	183.2±2.31	192.4±2.10	198.2±2.10	203.2±2.04
Standard	174.1±2.20	154.2±1.37^∗∗	145.6±2.03^∗∗∗	128.2±2.53^∗∗∗	107.1±1.10^∗∗∗
FT (100 mg/kg)	176.1±1.20	170.1±2.02^∗	164.2±1.22^∗∗	160.4±1.00^∗∗	156.6±2.67^∗∗
FT (300 mg/kg)	172.5±2.57	155.2±1.42^∗∗	145.3±1.10^∗∗∗	128.4±2.17^∗∗∗	113.1±3.53^∗∗∗
FO (100 mg/kg)	176.8±3.10	174.3±1.12^∗	167.5±1.20^∗∗	163.0±1.01^∗∗	158.2±2.60^∗∗
FO (300 mg/kg)	173.1±1.53	157.1±1.10^∗∗	146.9±2.23^∗∗∗	128.6±1.10^∗∗∗	118.7±1.51^∗∗∗

Values are mean ± SEM; 𝑁=6. ^∗𝑃<0.05, ^∗∗𝑃<0.001, and ^∗∗∗𝑃<0.0001 versus diabetic control.