Research Article

Wen-Dan Decoction Improves Negative Emotions in Sleep-Deprived Rats by Regulating Orexin-A and Leptin Expression

Table 3

WDD treatment ameliorated SD-induced increases in Cm and Rm times.

ParametersGroupsBefore SD7 days after SD14 days after SD

Cm timesControl group40.9 ± 19.731.3 ± 23.18.8 ± 4.4
Model group50.2 ± 11.489.0 ± 21.3**53.3 ± 15.6**
Diazepam group39.4 ± 16.5105.4 ± 15.0**44.4 ± 22.8**
WDD group45.7 ± 23.896.6 ± 35.7**25.0 ± 12.7*▲★★

Rm timesControl group7.7 ± 4.42.1 ± 1.81.0 ± 1.0
Model group6.4 ± 2.29.8 ± 2.5**4.0 ± 2.1**
Diazepam group5.3 ± 3.510.6 ± 4.8**4.3 ± 1.2**
WDD group6.8 ± 3.711.4 ± 2.5**2.0 ± 0.9*▲

, : versus the control group; : versus the model group; ★★ : versus the diazepam group.