Protective Effect and Mechanism of Total Flavones from Rhododendron simsii Planch on Endothelium-Dependent Dilatation and Hyperpolarization in Cerebral Ischemia-Reperfusion and Correlation to Hydrogen Sulphide Release in Rats

Figure 3

Effects of TFR on the levels of endothelium cells of middle cerebral artery CSE mRNA expression in rats subjected to cerebral ischemia-reperfusion. A: sham, B: NS, C~E: 25, 50, and 100 mg/kg TFR, and F: 37.5 mg/kg PPG + 100 mg/kg TFR. All values are presented as means ± SE. All comparisons were assessed by unpaired Student’s 𝑡-test. ^∗∗𝑃<0.01 compared with sham group, ^##𝑃<0.01 compared with NS group, and ^▲▲𝑃<0.01 compared with TFR (100 mg/kg) group.

(a)

(b)