De Qi, a Threshold of the Stimulus Intensity, Elicits the Specific Response of Acupoints and Intrinsic Change of Human Brain to Acupuncture

Table 2

Deactivated regions in fMRI after de qi in Zusanli acupoint following acupuncture.

Anatomy	BA	Side	Talairach			score
			(mm)	(mm)	(mm)
Posterior central gyrus	2/3	L/R	−16	−42	68	5.63
			52	−24	18	5.33
Superior temporal gyrus	22/52	R	58	2	0	5.29
			58	10	−4	4.78
Putamen		L/R	−28	2	6	5.26
			−26	−8	8	5.04
			22	2	−2	3.99
Insular lobe		L	−45	22	18	4.55
			−36	−18	12	4.06
Inferior parietal lobule	40	L/R	−50	−34	22	5.14
			58	−42	22	4.03
			50	−44	24	4.00
Culmen cerebelli		L/R	8	−56	−8	4.72
			−2	−46	−10	4.27
Intercerebral fissure		L/R	−2	−62	0	4.21
			2	−34	22	3.36
Clivas		L/R	−2	−60	−18	3.51
			36	−70	−28	4.51
			26	−82	−28	4.06
			16	−86	−28	3.85
Gyrus frontalis medius	6	R	−2	−24	64	4.57
	9/45	R	48	6	30	3.99
			56	18	26	3.56
Dentate body of cerebellum		R	14	−58	−34	4.56
Mesencephalon		L	−10	−26	−8	4.45
Thalamus		L/R	−4	−12	2	3.63
			14	−28	0	3.32
Cingulate gyrus	24	L/R	4	0	28	4.08
			−12	0	34	3.86
Corpus callosum		R	2	−4	20	4.27
Midtemporal gyrus	21	R	54	−60	6	4.10
Occipital lobe	18/19	L/R	−52	−70	4	3.78
			34	−82	12	3.50
Subthalamic nucleus		L	−8	−14	−8	3.44

Table 2 shows the Talairach coordinates. Numbers in cortical areas of the images correspond to Brodmann areas. Deactivation was noted bilaterally in posterior central gyrus (Brodmann areas 2 and 3), putamen, inferior parietal lobule (Brodmann areas 40), culmen cerebelli, intercerebral fissure, clivas, thalamus, cingulate gyrus (Brodmann areas 24), and occipital lobe (Brodmann areas 18 and 19). In addition, deactivation also occurred in the contralateral insular lobe, the contralateral mesencephalon, the contralateral subthalamic nucleus, the ipsilateral superior temporal gyrus (Brodmann areas 22 and 52), the ipsilateral gyrus frontalis medius (Brodmann areas 6, 9, and 45), the ipsilateral dentate body of cerebellum, the ipsilateral corpus callosum, and the ipsilateral midtemporal gyrus (Brodmann areas 21).