Electroacupuncture Improves Trinitrobenzene Sulfonic Acid-Induced Colitis, Evaluated by Transcriptomic Study

Table 2

Pathway analysis of genes in colonic tissues and spleens treated with TNBS and EA (100 Hz) at PC3 and PC6 acupoints.

Pathways^a	𝑃 value^b
	Colonic tissue	Spleen
Inflammation-associated pathways
IL-1 signaling pathway	0.00251	0.00841
IL-1𝛽 signaling pathway	0.00567	0.08017
Interleukin signaling pathway	0.01007	0.06366
IL-11 signaling pathway	0.01198	0.28622
TGF-𝛽 signaling pathway	0.00118	0.00014
TNF signaling pathway	0.06086	0.00077
Immunity-associated pathways
B cell receptor signaling pathway	0.13946	2.88×10^−9
Toll-like receptor signaling pathway	0.00295	9.69×10^−7
T cell receptor signaling pathway	0.34349	5.73×10^−6

aPathways which were associated with inflammation and immunity and were affected significantly either in colons or spleens are shown.
^b𝑃 values were calculated by the geneSetTest function implemented in the limma package.