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Evidence-Based Complementary and Alternative Medicine
Volume 2014, Article ID 969482, 11 pages
http://dx.doi.org/10.1155/2014/969482
Research Article

Naja naja atra Venom Protects against Manifestations of Systemic Lupus Erythematosus in MRL/lpr Mice

Department of Pharmacology and Laboratory of Aging and Nervous Diseases, Jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases, Soochow University School of Pharmaceutical Science, Suzhou 215123, China

Received 22 December 2013; Revised 3 June 2014; Accepted 10 June 2014; Published 30 June 2014

Academic Editor: Adair Santos

Copyright © 2014 Jiali Zhu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

In the pilot study, six MRL/lpr mice were divided into three groups: model and NNAV (30, 100 µg/kg), respectively. All mice were administrated for 16 weeks. The photographs on skin condition were taken with Olympus digtal camera (C5050Z; Olymus, Tokyo, Japan) at the age of 24 weeks when the skin lesions appeared, and the proteinuria were measured with Multistix8 strips (Global Biotech Co., Ltd., Guangzhou, China) during the experiment.

  1. Supplementary Material