Evidence-Based Complementary and Alternative Medicine

Research Article

Hexane Fractions of Bupleurum falcatum L. Stimulates Glucagon-Like Peptide-1 Secretion through -Mediated Pathway

Table 1

List of genes related to the GPCR signaling pathway which is regulated after HFBF treatment.
Probe nameDescriptionGene symbol valueFold change
Inositol 1,4,5-trisphosphate
A_33_P3298128Inositol 1,4,5-trisphosphate receptor, type 2 (ITPR2), mRNA [NM_002223]ITPR2 0.004 1.66
Adenylate cyclase
A_23_P126313Adenylate cyclase 10 (soluble) (ADCY10), transcript variant 1, mRNA [NM_018417]ADCY1 0.262−0.30
Phosphodiesterase
A_24_P197537Phosphodiesterase 8B (PDE8B), transcript variant 1, mRNA [NM_003719]PDE8B 0.7777−0.04
A_33_P3244951Phosphodiesterase 8A (PDE8A), transcript variant 1, mRNA [NM_002605]PDE8A 0.397−0.14
A_33_P3301940Phosphodiesterase 7B (PDE7B), mRNA [NM_018945]PDE7B 0.238−0.22
A_33_P3240552Phosphodiesterase 4D, cAMP-specific [Source: HGNC Symbol; Acc: 8783] [ENST00000509355]PDE4D 0.474−0.08
A_33_P3389649Phosphodiesterase 4D, cAMP-specific (PDE4D), transcript variant 4, mRNA [NM_001197218]PDE4D 0.167−0.23
A_33_P3389653Phosphodiesterase 4D, cAMP-specific (PDE4D), transcript variant 3, mRNA [NM_001165899]PDE4D 0.289−0.15
A_33_P3759611Phosphodiesterase 4C, cAMP-specific (PDE4C), transcript variant 1, mRNA [NM_000923]PDE4C 0.110−0.32
A_23_P74278Phosphodiesterase 4B, cAMP-specific (PDE4B), transcript variant d, mRNA [NM_001037341]PDE4B 0.039−0.20
A_24_P322474Phosphodiesterase 4A, cAMP-specific (PDE4A), transcript variant 4, mRNA [NM_006202]PDE4A 0.336−0.23
A_23_P401106Phosphodiesterase 2A, cGMP-stimulated (PDE2A), transcript variant 1, mRNA [NM_002599]PDE2A 0.511−0.06