Clinical Study on Prospective Efficacy of All-Trans Acid, Realgar-Indigo Naturalis Formula Combined with Chemotherapy as Maintenance Treatment of Acute Promyelocytic Leukemia

Table 2

Toxicity profile in two groups.

Parameters	Experimental group (𝑛=52)		Control group (𝑛=46)
Grade	1-2	3-4	1-2	3-4
Neutropenia	12	40	14	0
Liver damage	6	0	12	3
Renal damage	0	0	0	0
Cardiac damage	0	0	0	0
Gastrointestinal symptom	5	0	4	0
Oral ulcer	0	0	7	0

Neutropenia was higher in experimental group (𝑃=0), while liver damage is higher in control group (𝑃=0.0112).