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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 103570, 9 pages
http://dx.doi.org/10.1155/2015/103570
Research Article

The Anti-Inflammatory Actions of Auricular Point Acupressure for Chronic Low Back Pain

1School of Nursing, University of Pittsburgh, Pittsburgh, PA 15213, USA
2Department of Biostatistics, University of Texas, School of Public Health at San Antonio Regional Campus, University of Texas Health Science Center at San Antonio Regional Campus, Research to Advance Community Health Center, Houston, TX 77025, USA
3Division of General Internal Medicine, Department of Medicine, School of Medicine, University of Pittsburgh and Geriatric Research Education and Clinical Center, Veterans Administration Pittsburgh Healthcare System, Pittsburgh, PA 15213, USA
4Departments of Psychiatry, Physical Medicine, and Rehabilitation, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA
5Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA 15213, USA

Received 12 December 2014; Revised 1 March 2015; Accepted 2 March 2015

Academic Editor: Vincenzo De Feo

Copyright © 2015 Wei-Chun Lin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. Dagenais, J. Caro, and S. Haldeman, “A systematic review of low back pain cost of illness studies in the United States and internationally,” The Spine Journal, vol. 8, no. 1, pp. 8–20, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. J. K. Freburger, G. M. Holmes, R. P. Agans et al., “The rising prevalence of chronic low back pain,” Archives of Internal Medicine, vol. 169, no. 3, pp. 251–258, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. T. W. Strine and J. M. Hootman, “US national prevalence and correlates of low back and neck pain among adults,” Arthritis Care & Research, vol. 57, no. 4, pp. 656–665, 2007. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Haldeman and S. Dagenais, “What have we learned about the evidence-informed management of chronic low back pain?” The Spine Journal, vol. 8, no. 1, pp. 266–277, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. D. M. Eisenberg, R. B. Davis, S. L. Ettner et al., “Trends in alternative medicine use in the United States, 1990–1997: results of a follow-up national survey,” The Journal of the American Medical Association, vol. 280, no. 18, pp. 1569–1575, 1998. View at Publisher · View at Google Scholar · View at Scopus
  6. A. J. Vickers, A. M. Cronin, A. C. Maschino et al., “Acupuncture for chronic pain: individual patient data meta-analysis,” Archives of Internal Medicine, vol. 172, no. 19, pp. 1444–1453, 2012. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Ammendolia, A. D. Furlan, M. Imamura, E. Irvin, and M. van Tulder, “Evidence-informed management of chronic low back pain with needle acupuncture,” The Spine Journal, vol. 8, no. 1, pp. 160–172, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. L. C. Huang, Auricular Medicine: A Complete Manual of Auricular Diagnosis and Treatment, Auricular International Research & Training, Orlando, Fla, USA, 1st edition, 2005.
  9. T. Oleson, Auriculotherapy Manual: Chinese and Western Systems of Ear Acupuncture, Churchill Livingstone, Elsevier, Edinburgh, Scotland, 4th edition, 2014.
  10. P. Nogier, Treatise of Auriculotherapy, Maisonneuve, Moulins-lès-Metz, France, 1972.
  11. World Health Organization, WHO Report of the Working Group on Auricular Nomenclature, World Health Organization, Lyon, France, 1990.
  12. C. H. Yeh, L. C. Chien, D. Balaban et al., “A randomized clinical trial of auricular point acupressure for chronic low back pain: a feasibility study,” Evidence-Based Complementary and Alternative Medicine, vol. 2013, Article ID 196978, 9 pages, 2013. View at Publisher · View at Google Scholar · View at Scopus
  13. C.-H. Yeh, L.-C. Chien, Y.-C. Chiang, and L.-C. Huang, “Auricular point acupressure for chronic low back pain: a feasibility study for 1-week treatment,” Evidence-based Complementary and Alternative Medicine, vol. 2012, Article ID 383257, 9 pages, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. C. H. Yeh, N. E. Morone, L. C. Chien et al., “Auricular point acupressure to manage chronic low back pain in older adults: a randomized controlled pilot study,” Evidence-Based Complementary and Alternative Medicine, vol. 2014, Article ID 375173, 11 pages, 2014. View at Publisher · View at Google Scholar
  15. C. H. Yeh, L. K. P. Suen, J. Shen et al., “Changes in sleep with auricular point acupressure for chronic low back pain,” Behavioral Sleep Medicine. In press.
  16. L. K. P. Suen and E. M. C. Wong, “Longitudinal changes in the disability level of the elders with low back pain after auriculotherapy,” Complementary Therapies in Medicine, vol. 16, no. 1, pp. 28–35, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. L. R. Watkins and S. F. Maier, “The pain of being sick: implications of immune-to-brain communication for understanding pain,” Annual Review of Psychology, vol. 51, pp. 29–57, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. A. Starkweather, L. Witek-Janusek, and H. L. Mathews, “Neural-immune interactions: implications for pain management in patients with low-back pain and sciatica,” Biological Research for Nursing, vol. 6, no. 3, pp. 196–206, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. J. M. Cuellar, S. R. Golish, M. W. Reuter et al., “Cytokine evaluation in individuals with low back pain using discographic lavage,” The Spine Journal, vol. 10, no. 3, pp. 212–218, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. D. Borsook, L. Becerra, and R. Hargreaves, “Biomarkers for chronic pain and analgesia. Part 1: the need, reality, challenges, and solutions,” Discovery Medicine, vol. 11, no. 58, pp. 197–207, 2011. View at Google Scholar · View at Scopus
  21. G. D. Slade, M. S. Conrad, L. Diatchenko et al., “Cytokine biomarkers and chronic pain: association of genes, transcription, and circulating proteins with temporomandibular disorders and widespread palpation tenderness,” Pain, vol. 152, no. 12, pp. 2802–2812, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. J.-M. Zhang and J. An, “Cytokines, inflammation, and pain,” International Anesthesiology Clinics, vol. 45, no. 2, pp. 27–37, 2007. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Biyani and G. B. J. Andersson, “Low back pain: pathophysiology and management,” The Journal of the American Academy of Orthopaedic Surgeons, vol. 12, no. 2, pp. 106–115, 2004. View at Google Scholar · View at Scopus
  24. L. M. Pedersen, E. Schistad, L. M. Jacobsen, C. Røe, and J. Gjerstad, “Serum levels of the pro-inflammatory interleukins 6 (IL-6) and -8 (IL-8) in patients with lumbar radicular pain due to disc herniation: a 12-month prospective study,” Brain, Behavior, and Immunity, 2015. View at Publisher · View at Google Scholar
  25. P. Andrade, G. Hoogland, M. A. Garcia, H. W. Steinbusch, M. A. Daemen, and V. Visser-Vandewalle, “Elevated IL-1β and IL-6 levels in lumbar herniated discs in patients with sciatic pain,” European Spine Journal, vol. 22, no. 4, pp. 714–720, 2013. View at Publisher · View at Google Scholar · View at Scopus
  26. P. M. Torre and S. P. Oliver, “Inhibition of bovine peripheral blood mononuclear cell blastogenesis by fractionated mammary secretion,” Comparative Biochemistry and Physiology—Part B: Biochemistry and, vol. 92, no. 1, pp. 157–165, 1989. View at Publisher · View at Google Scholar · View at Scopus
  27. C. Heijmans-Antonissen, F. Wesseldijk, R. J. M. Munnikes et al., “Multiplex bead array assay for detection of 25 soluble cytokines in blister fluid of patients with complex regional pain syndrome type 1,” Mediators of Inflammation, vol. 2006, Article ID 28398, 8 pages, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. E. Krock, D. H. Rosenzweig, A.-J. Chabot-Doré et al., “Painful, degenerating intervertebral discs up-regulate neurite sprouting and CGRP through nociceptive factors,” Journal of Cellular and Molecular Medicine, vol. 18, no. 6, pp. 1213–1225, 2014. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Benemei, P. Nicoletti, J. G. Capone, and P. Geppetti, “CGRP receptors in the control of pain and inflammation,” Current Opinion in Pharmacology, vol. 9, no. 1, pp. 9–14, 2009. View at Publisher · View at Google Scholar · View at Scopus
  30. M. Tsuruoka, J. Tamaki, M. Maeda, B. Hayashi, and T. Inoue, “Biological implications of coeruleospinal inhibition of nociceptive processing in the spinal cord,” Frontiers in Integrative Neuroscience, vol. 6, article 87, 2012. View at Publisher · View at Google Scholar · View at Scopus
  31. R. D. Granstein, J. A. Wagner, L. L. Stohl, and W. Ding, “Calcitonin gene-related peptide: key regulator of cutaneous immunity,” Acta Physiologica, vol. 213, no. 3, pp. 586–594, 2015. View at Publisher · View at Google Scholar
  32. C.-L. Lu, P. J. Pasricha, J.-C. Hsieh et al., “Changes of the neuropeptides content and gene expression in spinal cord and dorsal root ganglion after noxious colorectal distension,” Regulatory Peptides, vol. 131, no. 1–3, pp. 66–73, 2005. View at Publisher · View at Google Scholar · View at Scopus
  33. D. S. Jessop, “β-endorphin in the immune system—mediator of pain and stress?” The Lancet, vol. 351, no. 9119, pp. 1828–1829, 1998. View at Publisher · View at Google Scholar · View at Scopus
  34. D. Alimi, A. Geissmann, and D. Gardeur, “Auricular acupuncture stimulation measured on functional magnetic resonance imaging,” Medical Acupuncture, vol. 13, pp. 18–21, 2002. View at Google Scholar
  35. Z.-Q. Zhao, “Neural mechanism underlying acupuncture analgesia,” Progress in Neurobiology, vol. 85, no. 4, pp. 355–375, 2008. View at Publisher · View at Google Scholar · View at Scopus
  36. F. J. Zijlstra, I. van den Berg-de Lange, F. J. P. M. Huygen, and J. Klein, “Anti-inflammatory actions of acupuncture,” Mediators of Inflammation, vol. 12, no. 2, pp. 59–69, 2003. View at Publisher · View at Google Scholar · View at Scopus
  37. H.-W. Kim, D.-H. Roh, S.-Y. Yoon et al., “The anti-inflammatory effects of low- and high-frequency electroacupuncture are mediated by peripheral opioids in a mouse air pouch inflammation model,” Journal of Alternative and Complementary Medicine, vol. 12, no. 1, pp. 39–44, 2006. View at Publisher · View at Google Scholar · View at Scopus
  38. C. H. Yeh, L. C. Chien, K. M. Albers et al., “Function of auricular point acupressure in inducing changes in inflammatory cytokines during chronic low-back pain: a pilot study,” Medical Acupuncture, vol. 26, no. 1, pp. 31–39, 2014. View at Publisher · View at Google Scholar · View at Scopus
  39. C. S. Cleeland and K. M. Ryan, “Pain assessment: global use of the Brief Pain Inventory,” Annals of the Academy of Medicine Singapore, vol. 23, no. 2, pp. 129–138, 1994. View at Google Scholar · View at Scopus
  40. R. H. Dworkin, D. C. Turk, K. W. Wyrwich et al., “Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations,” The Journal of Pain, vol. 9, no. 2, pp. 105–121, 2008. View at Google Scholar
  41. M. Roland and J. Fairbank, “The Roland-Morris disability questionnaire and the Oswestry disability questionnaire,” Spine, vol. 25, no. 24, pp. 3115–3124, 2000. View at Publisher · View at Google Scholar · View at Scopus
  42. M. Roland and R. Morris, “A study of the natural history of back pain. Part I: development of a reliable and sensitive measure of disability in low-back pain,” Spine, vol. 8, no. 2, pp. 141–144, 1983. View at Publisher · View at Google Scholar · View at Scopus
  43. K. Jordan, K. M. Dunn, M. Lewis, and P. Croft, “A minimal clinically important difference was derived for the Roland-Morris disability questionnaire for low back pain,” Journal of Clinical Epidemiology, vol. 59, no. 1, pp. 45–52, 2006. View at Publisher · View at Google Scholar · View at Scopus
  44. SAS Institute, SAS OnlineDoc 9.2, SAS Institute, Cary, NC, USA, 2009.
  45. P. Andrade, G. Hoogland, M. A. Garcia, H. W. Steinbusch, M. A. Daemen, and V. Visser-Vandewalle, “Elevated IL-1b and IL-6 levels in lumbar herniated discs in patients with sciatic pain,” European Spine Journal, vol. 22, no. 4, pp. 714–720, 2013. View at Publisher · View at Google Scholar · View at Scopus
  46. S. Ohtori, M. Miyagi, Y. Eguchi et al., “Epidural administration of spinal nerves with the tumor necrosis factor-alpha inhibitor, etanercept, compared with dexamethasone for treatment of sciatica in patients with lumbar spinal stenosis: a prospective randomized study,” Spine, vol. 37, no. 6, pp. 439–444, 2012. View at Publisher · View at Google Scholar · View at Scopus
  47. S. Ohtori, M. Miyagi, Y. Eguchi et al., “Efficacy of epidural administration of anti-interleukin-6 receptor antibody onto spinal nerve for treatment of sciatica,” European Spine Journal, vol. 21, no. 10, pp. 2079–2084, 2012. View at Publisher · View at Google Scholar · View at Scopus
  48. D. C. Kraychete, R. K. Sakata, A. M. Issy, O. Bacellar, R. Santos-Jesus, and E. M. Carvalho, “Serum cytokine levels in patients with chronic low back pain due to herniated disc: analytical cross-sectional study,” Sao Paulo Medical Journal, vol. 128, no. 5, pp. 259–262, 2010. View at Publisher · View at Google Scholar · View at Scopus
  49. A. Koch, K. Zacharowski, O. Boehm et al., “Nitric oxide and pro-inflammatory cytokines correlate with pain intensity in chronic pain patients,” Inflammation Research, vol. 56, no. 1, pp. 32–37, 2007. View at Publisher · View at Google Scholar · View at Scopus
  50. L. R. Watkins and S. F. Maier, “Immune regulation of central nervous system functions: from sickness responses to pathological pain,” Journal of Internal Medicine, vol. 257, no. 2, pp. 139–155, 2005. View at Publisher · View at Google Scholar · View at Scopus
  51. L. R. Watkins, L. E. Goehler, J. Relton, M. T. Brewer, and S. F. Maier, “Mechanisms of tumor necrosis factor-α (TNF-α) hyperalgesia,” Brain Research, vol. 692, no. 1-2, pp. 244–250, 1995. View at Publisher · View at Google Scholar · View at Scopus
  52. R. Dantzer, J. C. O'Connor, G. G. Freund, R. W. Johnson, and K. W. Kelley, “From inflammation to sickness and depression: when the immune system subjugates the brain,” Nature Reviews Neuroscience, vol. 9, no. 1, pp. 46–56, 2008. View at Publisher · View at Google Scholar · View at Scopus
  53. C. Stein, “The control of pain in peripheral tissue by opioids,” The New England Journal of Medicine, vol. 332, no. 25, pp. 1685–1690, 1995. View at Publisher · View at Google Scholar · View at Scopus
  54. A. C. Hartwig, “Peripheral beta-endorphin and pain modulation,” Anesthesia Progress, vol. 38, no. 3, pp. 75–78, 1991. View at Google Scholar · View at Scopus
  55. J.-S. Han, “Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies,” Trends in Neurosciences, vol. 26, no. 1, pp. 17–22, 2003. View at Publisher · View at Google Scholar · View at Scopus
  56. W.-Z. Ma, Y.-M. Zhang, H. Yuan, and W.-Y. Wang, “Effects of balance-acupuncture stimulation of ‘back pain’ and ‘hip pain’ points on plasma beta-endorphin and ACTH contents in rats with lumbar disc herniation,” Acupuncture Research, vol. 36, no. 5, pp. 357–360, 2011. View at Google Scholar · View at Scopus
  57. C. A. Rocheleau, G. D. Webster, A. Bryan, and J. Frazier, “Moderators of the relationship between exercise and mood changes: gender, exertion level, and workout duration,” Psychology and Health, vol. 19, no. 4, pp. 491–506, 2004. View at Publisher · View at Google Scholar · View at Scopus
  58. R. Prasad and H. N. Bhargava, “Detection of β-endorphin in human blood. A study of performance characteristics of different radiometric systems,” Archives of Pathology & Laboratory Medicine, vol. 116, no. 8, pp. 827–830, 1992. View at Google Scholar · View at Scopus