Antioxidant and Anti-Inflammatory Activity Determination of One Hundred Kinds of Pure Chemical Compounds Using Offline and Online Screening HPLC Assay

Table 1

Free radical-scavenging capacities of antioxidant activity available measured with DPPH and ABTS assay on microwell plate.

Number	Compounds names	Compounds; purchased	Concentration; M (mol/L)	Radical scavenging (%)
				DPPH	ABTS
1	Albiflorin	Wako	208.13	−0.15 ± 0.39	0.14 ± 5.27
2	Alisol A	Wako	203.79	−0.47 ± 0.71	12.92 ± 0.86
3	Alisol B	Wako	211.55	−1.66 ± 0.23	12.78 ± 1.35
4	Amygdalin	KFDA	218.61	−0.85 ± 0.67	12.31 ± 0.03
5	Anthraquinone	Wako	480.28	0.12 ± 0.70	0.86 ± 5.12
6	Atractylenolide iii	Chem Faces	402.71	−2.07 ± 0.53	1.34 ± 8.29
7	Aucubin	Wako	288.74	−1.64 ± 0.79	1.22 ± 9.74
8	Baicalein	KFDA	370.04	95.84 ± 0.15	99.37 ± 0.12
9	Benzoic acid	Sigma	818.87	1.88 ± 0.42	3.80 ± 0.26
10	Berberine	Chem Faces	297.30	0.64 ± 0.43	84.68 ± 2.55
11	Berberine HCl	KFDA	268.95	−0.30 ± 0.30	8.74 ± 8.38
12	Caffeic acid	Sigma	555.06	95.91 ± 0.16	99.66 ± 0.24
13	Calycosin	Chem Faces	351.79	64.51 ± 0.59	99.19 ± 0.05
14	Catalpol	Wako	275.99	−2.55 ± 0.47	1.12 ± 9.62
15	Chrysin	Sigma	393.33	0.45 ± 0.53	99.13 ± 0.06
16	Cimifugin	Chem Faces	326.46	−0.89 ± 0.21	14.39 ± 1.81
17	Cinnamyl alcohol	Sigma	745.27	−0.03 ± 0.37	15.18 ± 0.75
18	cis-Inositol	Sigma	555.06	0.15 ± 0.26	0.54 ± 1.22
19	Costunolide	Sigma	430.44	2.86 ± 0.17	20.13 ± 8.74
20	Crocin	Sigma	102.36	24.43 ± 1.28	47.73 ± 0.67
21	Curcumin	Sigma	271.46	97.50 ± 0.63	99.97 ± 0.16
22	(+)-Catechin hydrate	TCI	344.51	94.50 ± 0.16	99.15 ± 0.06
23	1,8-Dihydroxy-3-methylanthraquinone	Sigma	393.33	−0.94 ± 0.54	2.09 ± 2.60
24	D-(−)-Lactic acid	Sigma	1110.12	2.51 ± 2.40	28.29 ± 0.74
25	D-(+)-Chiro-inositol	Sigma	555.06	0.49 ± 0.33	0.21 ± 0.45
26	Daidzein	Wako	393.33	0.52 ± 0.61	99.49 ± 0.49
27	Decursin	KFDA	304.54	−3.01 ± 0.91	0.97 ± 2.75
28	Decursinol	Chem Faces	406.07	−1.59 ± 1.03	15.12 ± 1.81
29	Dioscin	Sigma	115.07	−2.93 ± 1.30	0.43 ± 2.75
30	Diosgenin	Sigma	241.18	−1.38 ± 0.70	1.96 ± 9.24
31	D-Pinitol	Sigma	514.99	−2.27 ± 0.33	12.72 ± 1.85
32	6,7-Dimethylesculetin	RD Chemical	484.99	−2.74 ± 0.54	1.31 ± 0.21
33	(−)-Epicatechin	Sigma	344.51	94.51 ± 0.41	99.61 ± 0.16
34	(−)-Epigallocatechin gallate	Sigma	218.16	95.69 ± 0.14	99.51 ± 0.24
35	Eleutheroside B	Wako	268.55	−2.04 ± 1.02	1.97 ± 2.85
36	Emodin	TCI	370.04	2.20 ± 1.16	91.27 ± 1.39
37	Ephedrine-HCl	KFDA	495.81	−2.11 ± 1.52	0.00 ± 0.12
38	Ergosterol	Chem Faces	252.11	−1.65 ± 1.34	0.55 ± 9.46
39	Eugenol	Sigma	609.01	93.72 ± 0.12	99.91 ± 0.55
40	Evodiamine	KFDA	329.64	4.21 ± 1.55	40.76 ± 2.09
41	Ferulic acid	Sigma	514.99	95.12 ± 0.24	98.96 ± 0.27
42	Gallic acid hydrate	TCI	587.82	95.56 ± 0.03	101.30 ± 2.12
43	Geniposide	Chem Faces	257.49	−1.45 ± 0.90	1.22 ± 9.49
44	Genistein	TCI	370.04	−1.52 ± 0.30	98.50 ± 0.48
45	Genistin	Wako	231.28	2.23 ± 0.64	100.65 ± 0.03
46	Geraniol	Sigma	112.49	−2.43 ± 1.67	14.94 ± 0.95
47	Glabridin	Wako	308.29	42.20 ± 0.88	100.58 ± 0.04
48	Glimepiride	Sigma	203.82	−1.33 ± 0.63	7.84 ± 2.30
49	Glycyrrhetic acid	TCI	212.46	0.66 ± 0.65	10.23 ± 0.62
50	Glycyrrhizin	TCI	121.52	1.59 ± 1.96	12.36 ± 1.15
51	Gomisin A	KFDA	240.12	1.80 ± 0.28	1.74 ± 0.22
52	Gomisin N	KFDA	249.71	0.45 ± 0.51	3.80 ± 0.21
53	Hesperidin	KFDA	202.23	31.84 ± 0.37	100.21 ± 0.01
54	Hyperoside	Chem Faces	215.34	93.16 ± 0.25	99.62 ± 0.20
55	2′-Hydroxy-4′-methoxy-acetophenone	Sigma	601.76	−2.81 ± 0.28	99.73 ± 1.04
56	Icariin	TCI	147.78	3.82 ± 1.08	14.60 ± 0.12
57	Imperatorin	Chem Faces	369.99	−0.71 ± 2.31	0.74 ± 9.51
58	Isoimperatorin	Santa Cruz Biotech	369.99	0.27 ± 0.22	3.06 ± 2.17
59	Jujuboside A	Chem Faces	82.83	−1.63 ± 0.35	0.26 ± 9.74
60	Kaempferol	Chem Faces	349.36	95.02 ± 0.22	99.84 ± 0.41
61	Liquiritigenin	Chem Faces	390.24	12.26 ± 0.86	0.12 ± 0.68
62	Loganin	KFDA	256.16	2.62 ± 1.28	5.80 ± 0.62
63	Magnolol	KFDA	375.47	54.50 ± 0.12	77.74 ± 1.06
64	Mevinolin	Sigma	247.19	−0.26 ± 0.07	2.78 ± 0.69
65	Morroniside	China Lang Chem Inc.	246.08	7.11 ± 0.58	19.62 ± 1.83
66	Naringin	Sigma	172.26	3.05 ± 0.37	100.36 ± 0.05
67	Nodakenin	Chem Faces	244.86	0.68 ± 0.45	15.70 ± 1.92
68	Oleanolic acid	Wako	218.96	−0.37 ± 0.54	0.00 ± 0.12
69	Ononin	Sigma	232.34	2.23 ± 1.58	22.91 ± 1.89
70	Oxymatrine	Chem Faces	378.26	−1.63 ± 0.17	0.72 ± 8.85
71	Oxypeucedanin	Chem Faces	349.31	−0.11 ± 0.27	19.10 ± 2.38
72	Paeoniflorin	TCI	208.13	4.29 ± 1.43	22.03 ± 0.91
73	Paeonol	Sigma	601.79	0.99 ± 2.21	19.79 ± 2.35
74	Palmatine chloride hydrate	Sigma	257.82	2.57 ± 2.42	84.15 ± 2.43
75	Palmatine	Chem Faces	292.05	0.12 ± 0.23	68.05 ± 3.63
76	p-Coumaric acid	Sigma	609.16	8.89 ± 0.04	38.52 ± 0.84
77	Poncirin	KFDA	168.19	−1.44 ± 1.27	84.20 ± 3.66
78	Puerarin	Wako	240.17	9.89 ± 0.16	100.62 ± 0.06
79	Quercetin	Sigma	330.86	96.02 ± 0.08	100.18 ± 0.06
80	Quercetin 3--D-glucoside	Sigma	215.34	94.43 ± 0.02	99.94 ± 0.06
81	Quercitrin hydrate	Sigma	223.03	93.32 ± 0.04	99.12 ± 0.14
82	Rutaecarpine	KFDA	348.04	−1.41 ± 0.60	97.23 ± 0.63
83	Rutin hydrate	Sigma	163.79	93.57 ± 0.13	100.10 ± 0.02
84	Saikosaponin a	KFDA	128.04	−0.67 ± 0.79	16.17 ± 1.62
85	Salicylaldehyde	Sigma	818.87	2.07 ± 0.04	100.36 ± 0.05
86	Schisandrin	KFDA	231.21	−2.39 ± 0.89	10.29 ± 2.43
87	Sennoside A	KFDA	115.91	−3.09 ± 0.64	87.86 ± 3.21
88	Sequoyitol	GlycoSyn	514.99	−3.20 ± 1.37	10.28 ± 2.07
89	Sinapic acid	Fluka	445.99	94.84 ± 0.33	99.99 ± 0.23
90	Spinosin	Chem Faces	164.33	−0.96 ± 2.26	80.16 ± 2.20
91	Tetrandrine	Fluka	160.58	60.83 ± 2.11	100.28 ± 0.06
92	trans-Cinnamaldehyde	Sigma	756.66	2.83 ± 0.69	19.00 ± 1.37
93	trans-Cinnamic acid	Sigma	674.95	0.19 ± 0.15	0.02 ± 9.45
94	Uric acid	Sigma	594.85	40.37 ± 1.97	98.33 ± 0.31
95	Vanillylacetone	Sigma	514.85	93.78 ± 0.06	99.92 ± 0.24
96	Wogonin	KFDA	351.79	1.02 ± 0.51	100.57 ± 0.13
97	Wogonoside	Chem Faces	217.21	10.84 ± 0.10	98.62 ± 0.32
98	Ziyuglycoside I	Chem Faces	130.38	−1.71 ± 1.00	0.01 ± 9.85
99	Z-Ligustilide	Chem Faces	531.29	1.92 ± 0.76	68.69 ± 2.14
100	Ascorbic acid (Vitamin C)	Daejung	567.79	99.56 ± 0.89	99.89 ± 0.04