Research Article

Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model

Table 1

The effects of Cordyceps militaris fruit body extract on antioxidant status in serum of mice before and after swimming.

FemaleMale
CTRLCM (g/kg)Pro (g/kg) CTRLCM (g/kg)Pro (g/kg)
0.51.02.00.5 0.51.02.00.5

Before swimming
 MDA (nmol/mL)17.36 ± 5.2810.29 ± 3.2512.41 ± 4.019.20 ± 4.5512.90 ± 3.8138.70 ± 4.0420.5 ± 6.8124.76 ± 9.529.52 ± 3.3318.79 ± 4.91
 SOD (U/mL)96 ± 31103 ± 1399 ± 13100 ± 33126 ± 18116 ± 20113 ± 2495 ± 2089 ± 16120 ± 23
 GSH-Px (μmol/mL)81 ± 30132 ± 32156 ± 33149 ± 33150 ± 3460 ± 565 ± 23150 ± 36139 ± 42226 ± 34
After swimming
 MDA (nmol/mL)36.19 ± 4.4031.07 ± 5.9811.62 ± 5.9419.33 ± 4.7437.78 ± 10.0233.90 ± 4.2932.38 ± 5.8913.97 ± 4.8621.67 ± 5.2127.43 ± 3.94
 SOD (U/mL)76 ± 14106 ± 21127 ± 11123 ± 20110 ± 1573 ± 21140 ± 17134 ± 9102 ± 2282 ± 17
 GSH-Px (μmol/mL)132 ± 41247 ± 42280 ± 35256 ± 59350 ± 45138 ± 45269 ± 46320 ± 60295 ± 53387 ± 45

Treatment with Cordyceps militaris fruit body extract (0.5 g/kg, 1.0 g/kg, and 2.0 g/kg) and Rhodiola rosea (0.5 g/kg) for 2 weeks; before and after 20 min swimming, the levels of MDA and the activities of SOD and GSH-Px in serum in male and female mouse were detected. Values are expressed as mean ± S.D. ( = 6). and compared with control group.