Studies on the Antifatigue Activities of Cordyceps militaris Fruit Body Extract in Mouse Model
Table 2
The effects of Cordyceps militaris fruit body extract on liver antioxidant status in mice before and after swimming.
Female
Male
CTRL
CM (g/kg)
Pro (g/kg)
CTRL
CM (g/kg)
Pro (g/kg)
0.5
1.0
2.0
0.5
0.5
1.0
2.0
0.5
Before swimming
MDA (nmol/mg prot)
0.53 ± 0.18
0.40 ± 0.08
0.25 ± 0.07
0.27 ± 0.15
0.50 ± 0.23
0.50 ± 0.17
0.39 ± 0.10
0.31 ± 0.12
0.30 ± 0.11
0.51 ± 0.09
ROS (FI/g prot)
1988 ± 203
1728 ± 278
1645 ± 158
1488 ± 202
1702 ± 189
1836 ± 147
1680 ± 203
1687 ± 256
1598 ± 108
1806 ± 217
SOD (U/mg prot)
196 ± 55
197 ± 16
196 ± 7
194 ± 17
201 ± 18
199 ± 16
194 ± 20
180 ± 15
174 ± 9
199 ± 15
GSH-Px (mol/g prot)
22 ± 7
24 ± 5
28 ± 7
29 ± 6
24 ± 5
24 ± 5
26 ± 4
29 ± 6
29 ± 3
26 ± 5
After swimming
MDA (nmol/mg prot)
0.49 ± 0.075
0.36 ± 0.099
0.39 ± 0.104
0.21 ± 0.034
0.54 ± 10.02
0.76 ± 0.151
0.35 ± 0.089
0.43 ± 0.132
0.32 ± 0.082
0.50 ± 0.18
ROS (FI/g prot)
2128 ± 287
1928 ± 387
1351 ± 127
1288 ± 122
1601 ± 265
2158 ± 333
1590 ± 165
1580 ± 336
1317 ± 108
1606 ± 323
SOD (U/mg prot)
216 ± 73
196 ± 15
214 ± 84
323 ± 41
364 ± 94
146 ± 36
152 ± 47
231 ± 66
302 ± 35
349 ± 60
GSH-Px (mol/g prot)
37 ± 7
29 ± 7
31 ± 5
31 ± 10
46 ± 16
30 ± 5
34 ± 8
30 ± 3
30 ± 6
36 ± 8
Treatment with Cordyceps militaris fruit body extract (0.5 g/kg, 1.0 g/kg, and 2.0 g/kg) and Rhodiola rosea (0.5 g/kg) for 2 weeks; before and after 20 min swimming, the levels of MDA, ROS, and the activities of SOD and GSH-Px in liver in male and female mouse were detected. Values are expressed as mean ± S.D. ( = 6). and compared with control group.
