In Vitro Antimicrobial and Antiproliferative Activity of Amphipterygium adstringens
Table 2
Cell lines used in the evaluation of antiproliferative activity.
Cell line
Organ/disease
Origin tissue
Total growth inhibition (µg/mL)
CE
DOX
U251
CNS; glioma
Ectoderm
26.10
<0.025
UACC-62
Skin; melanoma
Ectoderm
7.30
0.028
NCI-ADR/RES
Ovary; adenocarcinoma
Ectoderm
26.40
>25.00
786-O
Kidney; adenocarcinoma
Mesoderm
28.00
0.038
NCI-H460
Lung; non-small-cell lung carcinoma
Mesoderm
27.50
<0.025
PC-3
Prostate; adenocarcinoma
Mesoderm
24.80
0.025
OVCAR-3
Ovary; adenocarcinoma
Mesoderm
4.40
0.230
HT-29
Colon; adenocarcinoma
Endoderm
7.90
0.026
K562
Bone marrow; chronic myeloid leukemia
Mesenchyme
>250
>25.00
Results are the mean ± SD of 3 replicates per treatment in three independent tests after 48 hours of treatment. CE: crude extract of Amphipterygium adstringens. DOX: doxorubicin (positive control). Multidrug resistant cell line.
