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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 186436, 9 pages
http://dx.doi.org/10.1155/2015/186436
Research Article

The Flavonoid Apigenin Ameliorates Cisplatin-Induced Nephrotoxicity through Reduction of p53 Activation and Promotion of PI3K/Akt Pathway in Human Renal Proximal Tubular Epithelial Cells

1Department of Pathology, College of Korean Medicine, Wonkwang University, Iksan, Jeonbuk 570-749, Republic of Korea
2Department of Pathology, Chonbuk National University Medical School, Research Institute of Clinical Medicine and Institute for Medical Sciences, Jeonju, Jeonbuk 561-756, Republic of Korea
3Department of Microbiology and Immunology, Wonkwang University School of Medicine, Iksan, Jeonbuk 570-749, Republic of Korea
4Department of Neuropsychiatry, College of Korean Medicine, Wonkwang University, Iksan, Jeonbuk 570-749, Republic of Korea
5Research Center of Traditional Korean Medicine, Wonkwang University, Iksan, Jeonbuk 570-749, Republic of Korea

Received 27 February 2015; Accepted 10 May 2015

Academic Editor: Jintanaporn Wattanathorn

Copyright © 2015 Sung Min Ju et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

How to Cite this Article

Sung Min Ju, Jun Gue Kang, Jun Sang Bae, Hyun Ock Pae, Yeoung Su Lyu, and Byung Hun Jeon, “The Flavonoid Apigenin Ameliorates Cisplatin-Induced Nephrotoxicity through Reduction of p53 Activation and Promotion of PI3K/Akt Pathway in Human Renal Proximal Tubular Epithelial Cells,” Evidence-Based Complementary and Alternative Medicine, vol. 2015, Article ID 186436, 9 pages, 2015. https://doi.org/10.1155/2015/186436.