ERK1/2 and HIF1α Are Involved in Antiangiogenic Effect of Polyphenols-Enriched Fraction from Chilean Propolis

Figure 4

Effect of EEP and Pn on formation of capillary-like structures from aortic ring under VEGF (10 ng/mL) stimulus. (a) Control aortic ring. (b) Aortic ring, DMSO (0.1%) treated. (c) Aortic ring, EEP treated (15 µg/mL). (d) Aortic ring, Pn treated (15 µg/mL). (e) Relative quantification of capillary-like structures. Data presented as mean standard deviation. ; . C: control; V: vehicle; Pn: Pinocembrin.

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