Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Fig 4

Research Article

Extra Virgin Olive Oil Polyphenols Promote Cholesterol Efflux and Improve HDL Functionality

Figure 4

Tyrosol and hydroxytyrosol increase ABCA1 protein expression and enhance apoA-I-mediated cholesterol efflux. [3H]-Cholesterol-loaded J774 macrophages were incubated for 12 h with different concentrations (0 to 25 μM) of tyrosol (a) or hydroxytyrosol (b) to generate ABCA1-enriched cells, which were then incubated with 25 μg/mL of apo-AI for 4 h. Results are expressed as the means ± SEM of at least three independent experiments.

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