Brain Network Response to Acupuncture Stimuli in Experimental Acute Low Back Pain: An fMRI Study

Table 2

fMRI signal changes evoked by ACUP (ACUP (ON status compared with OFF status)) one-sample -test analysis , FDR < 0.05.

	BA	Cluster sizes	Peak -score	Peak MNI coordinate
Left insula				13	52	−3.51	−42	−15	15
Left M1	6	48	−2.56	−36	10	10
Left S2	43	36	−3.01	−37	−12	2
Left frontal eye field	8	66	−3.26	−15	35	53
Left dlPFC	46	97	3.81	−39	36	18
Right M1	6	348	6.16	51	6	12
Left PAG		44	−3.26	−3	−30	−3
Left PHP		35	−3.02	0	−24	0
Left thalamus		26	−2.56	4	−30	−5
Right dmPFC	8	43	−3.98	15	33	45
Right supramarginal gyrus	40	55	4.87	63	−27	33
Right S1	2	40	3.97	55	−20	30
Right supramarginal gyrus	40	48	−3.28	54	−60	39
Right angular gyrus	39	40	−3.00	50	−60	30
Right lateral temporal cortex	21	34	−2.56	49	−55	26
Right pMCC	31	101	3.98	18	−24	39
Bilateral SMA		79	2.54	12	0	60
Right PHP	35	46	−4.00	24	−27	−18
Right HP		40	−3.89	25	−20	−20
Bilateral pACC	32	34	−3.42	0	33	21
Left dmPFC	24	30	−3.23	15	20	20

FDR: false discovery rate; MNI: Montreal Neurological Institute; M1: primary motor cortex; S2: secondary somatosensory cortex; dlPFC: dorsolateral prefrontal cortex, periaqueductal grey (PAG); PHP: parahippocampus; dmPFC: dorsomedial prefrontal cortex; S1: primary somatosensory cortex; pMCC: posterior mid-cingulate cortex; SMA: supplementary motor area; HP: hippocampus; pACC: pregenual anterior cingulate cortex.