A Special Extract of Bacopa monnieri (CDRI-08) Restores Learning and Memory by Upregulating Expression of the NMDA Receptor Subunit GluN2B in the Brain of Scopolamine-Induced Amnesic Mice

Table 1

Schedule for the vehicle/drug treatment and training on Radial Arm Maze paradigm.

Experimental Set	Group; ()	Treatment Schedule
		Day 1–7	Day 8–15	Day 16–21
Control	I	0.5% Tween 80 (150 min before) + NS (120 min before)
B. monnieri extract (CDRI-08)	II	0.5% Tween 80 (150 min before) + NS (120 min before)	B. monnieri extract (200 mg/Kg) in 0.5% Tween; 80 (150 min before) + NS (120 min before)
Scopolamine	III	0.5% Tween   80 (150 min before) + NS (120 min before)		Scopolamine (2 mg/Kg) in NS (120 min before) + 0.5% Tween 80 (150 min before)
Scopolamine + B. monnieri extract (CDRI-08)	IV	0.5% Tween 80 (150 min before) + Scopolamine (2 mg/Kg) in NS (120 min before)	B. monnieri extract (200 mg/Kg) in 0.5% Tween; 80 (150 min before) + NS (120 min before)

Note: NS-Normal saline; before-duration of time before behavioral recording.