Research Article

Sibjotang Increases Atrial Natriuretic Peptide Secretion in Beating Rabbit Atria

Figure 6

Effects of subtype-selective inhibitors of protein kinase C on the Sibjotang- (SJ-) induced increase in ANP secretion, pulse pressure, and stroke volume in atria. (a) Effects of inhibitors of protein kinase C on the SJ- (100 μg/mL) induced increase in ANP secretion. (b) Effects of inhibitors of protein kinase C on the SJ-induced increase in pulse pressure. (c) Effects of inhibitors of protein kinase C on the SJ-induced increase in stroke volume. Values are mean ± SE. Number of experiments: control, ; SJ (100 μg/mL), ; LY333531 (LY) 30 nM + SJ, ; LY 30 nM + vehicle, ; LY 100 nM + SJ, ; LY 100 nM + vehicle, ; GO6976 (GO) + SJ, ; GO + vehicle, ; Rottlerin (Rott) + SJ, ; and Rott + vehicle, . , versus SJ; , versus control.
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