Research Article

Aqueous Extract of Agaricus blazei Murrill Prevents Age-Related Changes in the Myenteric Plexus of the Jejunum in Rats

Table 4

Intestinal morphometry: total wall (TW), mucosa (MC), and muscle (MM) tunicae, villus height (VH), crypt depth (CD), metaphase index (MetI), and number of goblet cells (GLC) in the jejunum in aging rats (C7, C12, and C23 groups) and aging rats supplemented with the aqueous extract of A. blazei (CA12 and CA23 groups). The results are expressed as mean ± standard error.

C7C12CA12C23CA23

TW (µm)835.13 ± 1.97a*760.65 ± 2.32b805.95 ± 3.11c802.91 ± 6.52c806.29 ± 2.86c
MC (µm)700.85 ± 2.20a639.61 ± 2.24b674.99 ± 3.24c648.92 ± 5.56b641.19 ± 2.19b
MM (µm)100.8 ± 0.59a101.1 ± 0.89a98.61 ± 0.67a103.2 ± 0.82a 113.9 ± 1.13b
VH (µm)494.03 ± 1.75a449.10 ± 2.52b464.42 ± 2.36c458.05 ± 3.23c420.02 ± 2.91d
CD (µm)274.20 ± 1.72a218.61 ± 1.15b212.31 ± 1.14c244.00 ± 1.56d235.50 ± 1.36e
MetI (%)7.59 ± 0.35a6.78 ± 0.57a6.74 ± 0.34a7.42 ± 0.52a7.53 ± 0.32a
GLC#72.09 ± 2.49a75.34 ± 2.99a74.48 ± 2.59a53.07 ± 1.88b60.98 ± 1.86b

Different letters in the same line indicate significant statistical difference (). #Values expressed as goblet cells per field.