Research Article
Anti-Inflammatory Activity of Triterpenes Isolated from Protium paniculatum Oil-Resins
Table 1
Cell viability of J774 cells treated with 5, 10, and 20 μg/mL of isolated triterpenes for 24, 48, and 72 hours.
| | 24 hours | 48 hours | 72 hours | Concentration (µg/mL) | 20 | 10 | 5 | 20 | 10 | 5 | 20 | 10 | 5 | | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE | Mean ± SE |
| α,β-Amyrin | 57.3 ± 1.9 | 86.4 ± 0.8 | 105.8 ± 2.3 | 36.4 ± 3.1 | 88,5 ± 2.8 | 110.0 ± 2.5 | 37.1 ± 3.5 | 88.7 ± 1.2 | 97.2 ± 1.8 |
Acetylated α,β-amyrin | 87.1 ± 0.5 | 152.9 ± 0.7 | 124.4 ± 1.9 | 32.1 ± 2.4 | 99.5 ± 3.6 | 125.0 ± 1.7 | 47.7 ± 1.9 | 98.0 ± 2.9 | 103.5 ± 2.7 | α,β-Amyrone | 119.4 ± 0.5 | 153.8 ± 1.8 | 144.0 ± 0.78 | 81.9 ± 2.9 | 126.7 ± 0.7 | 133.5 ± 1.5 | 65.3 ± 1.7 | 102.0 ± 0.7 | 105.2 ± 3.5 | Brein/maniladiol | 40.6 ± 1.1 | 82.4 ± 1.9 | 97.2 ± 3.5 | 13.3 ± 2.0 | 47.6 ± 2.9 | 90.0 ± 1.2 | 5.4 ± 0.6 | 23.8 ± 3.1 | 80.2 ± 1.6 | Indomethacin | 100.1 ± 3.2 | 123.6 ± 2.9 | 117.5 ± 3.7 | 50.5 ± 2.8 | 100.8 ± 1.3 | 105.9 ± 0.8 | 57.9 ± 1.1 | 102.3 ± 1.7 | 103.8 ± 2.9 | Doxorubicin | 26.0 ± 0.4 | 27.3 ± 1.2 | 25.7 ± 2.6 | 9.3 ± 1.4 | 10.0 ± 0.1 | 10.1 ± 0.2 | 3.8 ± 0.7 | 3.9 ± 0.07 | 3.9 ± 0.1 | DMSO | 70.8 ± 0.7 | 108.6 ± 0.6 | 113.3 ± 0.6 | 38.9 ± 0.2 | 98.9 ± 2.7 | 109.5 ± 2.9 | 33.4 ± 2.3 | 98.6 ± 1.1 | 99.0 ± 1.3 | Medium | 106.1 ± 4.0 | 100.0 ± 9.7 | 101.30 ± 1.5 | 106.7 ± 1.8 | 101.9 ± 11.0 | 103.4 ± 2.1 | 99.9 ± 4.8 | 98.9 ± 3.4 | 95.4 ± 4.2 |
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Notes. Data are presented as % mean ± standard error (). SE: standard error; DMSO: dimethyl sulfoxide.
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