Antimicrobial, Antioxidant, Anti-Inflammatory, and Cytotoxic Activities of Propolis from the Stingless Bee Tetragonisca fiebrigi (Jataí)

Figure 4

Cytotoxic action of EEP from T. fiebrigi against the K562 erythroleukemia cell line. (a) Representative diagrams obtained by flow cytometry of cells stained with annexin V-FITC/PI: the lower left quadrant (PI⁻/An⁻) represents the viable cells; the lower right quadrant (PI⁻/An⁺) represents the apoptotic cells; the upper left quadrant (PI⁺/An⁻) represents cells in necrosis; and the upper right quadrant (PI⁺/An⁺) represents cells in secondary necrosis. (b) Frequency of cell death, obtained from the corresponding diagrams of tested concentrations. ^* treated group versus control viable cells. treated group versus control necrosis.

(a)

(b)