Ginkgolide C Suppresses Adipogenesis in 3T3-L1 Adipocytes via the AMPK Signaling Pathway

Figure 2

Effects of ginkgolide C (GC) on transcription factors of adipogenesis in differentiated 3T3-L1 adipocytes. (a) Differentiated 3T3-L1 cells were treated with various concentrations of ginkgolide C for 24 h and PPAR-α, PPAR-γ, C/EBPα, C/EBPβ, and SREBP-1c proteins were detected by western blot ( per group). β-actin expression was used as an internal control. ((b) and (c)) Real-time PCR results showing transcription factor gene expression. The fold expression levels were measured relative to the expression of β-actin (internal control). Data are presented as the mean ± SD; , , compared to differentiated 3T3-L1 cells (control group).

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