Huqi San-Evoked Rat Colonic Anion Secretion through Increasing CFTR Expression

Figure 4

Effects of the RA and RP on the in the mucosa/submucosa preparations of the rat distal colon. The scattergram illustrates the application of different concentrations of RA (0.15, 0.3, 0.75, and 1.5 mg/mL) on the responses (a). Summary of the effects of different concentration of RA on the transepithelial resistance in the dosage of RA (1.5 mg/mL) significantly reduced colonic transepithelial resistance (b). The effect of different concentrations of RA (0.15, 0.3, 0.75, and 1.5 mg/mL) on the distal colon mucosa . Arrowheads indicate the time of RA addition (c). The scattergram illustrates the application of different concentrations of RP (0.1, 1.0, 10.0, and 100 mg/mL) on the responses (d). Summary of the effects of different concentration of RP on the transepithelial resistance higher dosage of RP (1.0, 10.0, and 100.0 mg/mL) had no significant changes on colonic transepithelial resistance (e). The effect of different concentrations of RP (0.1, 1.0, 10.0, and 100.0 mg/mL) on the distal colon mucosa . Arrowheads indicate the time of RP addition (f). Unpaired -test was used. Data represents mean ± S.E.M., ,  when compared with control group alone.

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