Prophylactic Treatment with Adlay Bran Extract Reduces the Risk of Severe Acute Radiation Dermatitis: A Prospective, Randomized, Double-Blind Study
Table 1
Demographic and clinical characteristics of patients in the adlay bran extract and placebo groups.
Adlay bran group ()
Placebo group ()
value
Age (mean ± SD)
51.2 ± 10.5
52.1 ± 9.2
0.672
Body mass index (mean ± SD)
22.4 ± 3.2
23.2 ± 2.8
0.247
Education
0.933
Junior high school or lower
19 (26.0%)
9 (24.3%)
Senior high school
25 (34.2%)
14 (37.8%)
College or above
29 (39.7%)
14 (37.8%)
Marital status
0.822
Single
9 (12.3%)
4 (10.8%)
Married
50 (68.5%)
24 (64.9%)
Widowed or divorced
14 (19.2%)
9 (24.3%)
Annual income (TWD)
0.329
<400,000
30 (41.1%)
13 (35.1%)
400,000–800,000
16 (21.9%)
13 (35.1%)
>800,000
27 (37.0%)
11 (29.7%)
Breast cancer stage
0.326
0
11 (15.1%)
3 (8.1%)
I
30 (41.1%)
17 (45.9%)
II
15 (20.5%)
12 (32.4%)
III
17 (23.3%)
5 (13.5%)
Diabetes mellitus
0.730
Yes
6 (8.2%)
4 (10.8%)
No
67 (91.8%)
33 (89.2%)
Hypertension
1.000
Yes
9 (12.3%)
5 (13.5%)
No
64 (87.7%)
32 (86.5%)
Pretreatment hemoglobin level
11.99 ± 1.26
11.91 ± 1.29
0.748
Pretreatment creatinine level
0.734 ± 0.908
0.628 ± 0.114
0.482
Pretreatment fasting cholesterol level
193.1 ± 37.0
195.7 ± 45.0
0.750
Pretreatment fasting triglyceride level
113.3 ± 78.9
136.9 ± 104.1
0.188
Surgery
0.190
Breast conserving surgery
61 (83.6%)
27 (73.0%)
Modified radical mastectomy
12 (16.4%)
10 (27.0%)
Chemotherapy before radiotherapy
0.458
Yes
42 (57.5%)
24 (64.9%)
No
31 (42.5%)
13 (35.1%)
Hormone therapy
0.522
Yes
51 (69.9%)
28 (75.7%)
No
22 (30.1%)
9 (24.3%)
values were determined using the two-sample -test for continuous variables and the Chi-square or Fisher’s exact test for categorical variables. TWD: Taiwan Dollar (1 Taiwan Dollar = 0.0325 United States Dollar).
