Prophylactic Treatment with Adlay Bran Extract Reduces the Risk of Severe Acute Radiation Dermatitis: A Prospective, Randomized, Double-Blind Study

Table 3

Univariate analysis to determine prognostic factors for the development of severe acute radiation dermatitis.

Factor	Skin reaction (RTOG)		value
	Grade ≤ 1; ()	Grade ≥ 2; ()
Age	50.3 ± 9.5	52.5 ± 10.4	0.246
Body mass index	21.6 ± 2.3	23.5 ± 3.3	<0.001
Diabetes mellitus			0.180
Yes	2 (4.1%)	8 (13.1%)
No	47 (95.9%)	53 (86.9%)
Hypertension			0.477
Yes	5 (10.2%)	9 (14.8%)
No	44 (89.8%)	52 (85.2%)
Pretreatment hemoglobin level	11.90 ± 1.24	12.01 ± 1.29	0.654
Pretreatment creatinine level	0.618 ± 0.178	0.764 ± 0.983	0.307
Surgery			0.565
Breast conserving surgery	38 (77.6%)	50 (82.0%)
Modified radical mastectomy	11 (22.4%)	11 (18.0%)
Chemotherapy			0.531
Yes	31 (63.3%)	35 (57.4%)
No	18 (36.7%)	26 (42.6%)
Hormone therapy			0.612
Yes	34 (69.4%)	45 (73.8%)
No	15 (30.6%)	16 (26.2%)

values were determined using the two-sample -test for continuous variables and the Chi-square or Fisher’s exact test for categorical variables.