Evidence-Based Complementary and Alternative Medicine / 2015 / Article / Tab 1

Research Article

Antioxidant, Antibacterial, Cytotoxic, and Anti-Inflammatory Potential of the Leaves of Solanum lycocarpum A. St. Hil. (Solanaceae)

Table 1

DPPH-scavenging activity, IC50 values, total flavonoids, and cytotoxic activity of ethanol extract and fractions from leaves of Solanum lycocarpum.

SamplesDPPH scavenging activityIC50 (μg/mL)TFCCC50 (95% CL)
1 μg/mL10 μg/mL100 μg/mL250 μg/mL500 μg/mLμg/mL

EE32.03 ± 0.42ab37.16 ± 0.34ab93.69 ± 0.23ab97.42 ± 0.06ab99.38 ± 0.27a36.63 ± 6.06ab8.40 ± 0.7410.20 ± 1.54
Hex38.66 ± 0.52a41.82 ± 0.64ab47.29 ± 0.58ab58.28 ± 0.91ab67.02 ± 0.69ab178.14 ± 33.63ab3.40 ± 0.4713.51 ± 3.72
DCM33.34 ± 0.24ab66.00 ± 0.17ab71.37 ± 0.62ab83.56 ± 0.83ab99.59 ± 0.19a4.29 ± 0.89ab168.00 ± 2.89165.70 ± 4.00
Ac43.48 ± 0.29ab65.73 ± 0.73ab76.65 ± 0.29ab92.43 ± 0.28ab97.10 ± 0.69ab1.82 ± 0.32a184.00 ± 1.739975.00 ± 5.41
HE32.09 ± 1.67ab65.88 ± 0.84ab87.80 ± 0.35ab91.91 ± 0.40b98.41 ± 0.05ab3.46 ± 0.45ab105.00 ± 1.1525.00 ± 2.01
BHT18.50 ± 0.2425.90 ± 0.6486.00 ± 0.5691.40 ± 0.2894.02 ± 0.6416.36 ± 1.63
AA 39.10 ± 0.3482.60 ± 0.2690.80 ± 0.3295.08 ± 0.4399.80 ± 0.581.62 ± 0.25

Ethanol extract (EE), hexane (Hex), dichloromethane (DCM), ethyl acetate (Ac), and hydroethanol (HE) fractions, 2,6-di-tert-butyl-4-methylphenol (BHT) and ascorbic acid (AA).
IC50: concentration (in μg/mL) of samples required to inhibit the formation of DPPH radicals by 50%.
TFC: total flavonoids content: results expressed as μg of rutin equivalents/mg of extract or fraction.
CC50: concentration that killed 50% of cells; CL: confidence limits.
Each value in the table is the mean ± standard deviation (). ap < 0.05 compared with BHT, bp < 0.05 compared with AA.

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