Research Article

[Retracted] Sagunja-Tang Improves Lipid Related Disease in a Postmenopausal Rat Model and HepG2 Cells

Table 2

Serum lipid levels in a rat model of menopausal hyperlipidemia.

ShamOVX-ConOVX-SVOVX-SGJT (50)OVX-SGJT (150)OVX-SGJT (450)
(n = 5)(n = 5)(n = 5)(n = 5)(n = 5)(n = 5)

T-CHO (mg/dL)113.50 ± 2.179221.25 ± 6.142178.50 ± 35.624bc147.00 ± 3.894c178.75 ± 0.081bc195.75 ± 18.6221ab
TG (mg/dL)46.6 ± 7.8064.06 ± 6.0648.33 ± 3.21a46.25 ± 4.66a60.00 ± 4.38a56.75 ± 10.56a
HDL (mg/dL)67.2 ± 4.0331.8 ± 4.541.6 ± 3.14b36.00 ± 2.71ab41.8 ± 8.31b44.00 ± 3.86b
LDL (mg/dL)37.52 ± 3.83176.64 ± 0.43127.23 ± 31.842bc101.89 ± 3.879c125.08 ± 17.947bc151.75 ± 15.823ab

Sham, Sham rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-Con, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-SV, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with simvastatin (20 mg/kg); OVX-SGJT, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with SGJT (50, 150, 450 mg/kg). After 8 weeks, the serum levels of TC, TG, HDL, and LDL were measured. Values are expressed as means ± SD (n = 5). Significantly different between the sham and OVX-Con at P < 0.01, (two-sample -test). Values not sharing a common alphabet as superscripts are significantly different from each other at the level of P < 0.05 (ANOVA followed by Duncan’s test).