[Retracted] Sagunja-Tang Improves Lipid Related Disease in a Postmenopausal Rat Model and HepG2 Cells

Table 3

Atherogenic index, cardiac risk factor, lumen diameter, and media thickness in a rat model of menopausal hyperlipidemia.

	Sham	OVX-Con	OVX-SV	OVX-SGJT (50)	OVX-SGJT (150)	OVX-SGJT (450)
	(n = 5)	(n = 5)	(n = 5)	(n = 5)	(n = 5)	(n = 5)
Atherogenic index	0.69 ± 0.09	6.05 ± 0.89	3.31 ± 0.80^b	3.10 ± 0.284^b	3.39 ± 0.884^b	3.47 ± 0.503^b
Cardiac risk factor	1.69 ± 0.09	7.05 ± 0.89	4.31 ± 0.80^b	4.1 ± 0.284^b	4.39 ± 0.885^b	4.47 ± 0.503^b
Lumen diameter (μm)	1,931.25 ± 2.86	847.78 ± 55.50	885.39 ± 74.43^ab	1,000.65 ± 83.5^bc	974.43 ± 47.84^abc	1,064.38 ± 81.55^c
Intima-media thickness (μm)	97.65 ± 12.65	217.66 ± 24.01	118.62 ± 11.93^b	121.44 ± 11.71^b	109.43 ± 9.41^b	114.61 ± 10.10^b
Lumen diameter/intima-media thickness	20.00 ± 2.26	3.75 ± 0.16	7.51 ± 0.86^b	8.29 ± 0.92^bc	8.95 ± 0.77^bc	9.34 ± 0.95^c

Sham, Sham rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-Con, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD); OVX-SV, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with simvastatin (20 mg/kg); OVX-SGJT, OVX rats fed a high-fat (HFD), high-cholesterol diet (HCD) supplemented with SGJT (50, 150, 450 mg/kg). After 8 weeks, their serum lipid levels were measured, followed by calculation of atherogenic index and cardiac risk factor scores (atherogenic index = (TC − HDL)/HDL, cardiac risk factor = TC/HDL). And lumen diameter and intima-media thickness were measured. Values are expressed as means ± SD (n = 5). Significantly different between the sham and OVX-Con at P < 0.01, (two-sample -test). Values not sharing a common alphabet as superscripts are significantly different from each other at the level of P < 0.05 (ANOVA followed by Duncan’s test).