Research Article

Toxicopathological Evaluation of Hydroethanol Extract of Dianthus basuticus in Wistar Rats

Table 2

Effect of administration of hydroethanol extract of Dianthus basuticus on some haematological parameters of male Wistar rats.

ParametersDose (mg/kg body weight/day)
Control200400800

White blood cell (×103/µL)7.77 ± 1.838.00 ± 0.986.87 ± 2.238.55 ± 2.47
Red blood cell (×106/µL)8.45 ± 0.238.91 ± 0.418.69 ± 0.318.84 ± 0.54
Haematocrit (%)0.46 ± 0.010.46 ± 0.020.47 ± 0.020.47 ± 0.02
Haemoglobin (g/dL)15.83 ± 0.1515.93 ± 0.6416.10 ± 0.7016.35 ± 0.64
MCV (fL)54.67 ± 0.5854.00 ± 0.0054.33 ± 1.1552.50 ± 0.71***
MCH (pg)18.67 ± 0.5818.00 ± 0.0018.67 ± 0.5818.30 ± 0.42
MCHC (g/dL)34.67 ± 0.5734.00 ± 0.0034.00 ± 1.0035.00 ± 0.0
RDW (fL)19.20 ± 1.1119.37 ± 0.4919.77 ± 1.0019.70 ± 1.56
Neutrophils (%)1.76 ± 0.471.72 ± 0.651.69 ± 0.681.32 ± 0.25
Lymphocytes (%)5.36 ± 1.365.72 ± 0.335.26 ± 1.476.55 ± 1.96*
Monocytes (%)0.32 ± 0.150.46 ± 0.110.37 ± 0.110.36 ± 0.08
Eosinophils (%)0.13 ± 0.040.11 ± 0.070.16 ± 0.040.31 ± 0.13
Basophils (%) 0.01 ± 0.000.01 ± 0.00 0.01 ± 0.01 0.02 ± 0.00
Platelets (×103/µL)914.67 ± 76.56881.33 ± 70.63872.00 ± 59.921006.50 ± 43.13***

Values are presented as mean ± SEM ().
*Statistically different from the control at .
***Statistically different from the control at .