Research Article
Toxicopathological Evaluation of Hydroethanol Extract of Dianthus basuticus in Wistar Rats
Table 2
Effect of administration of hydroethanol extract of Dianthus basuticus on some haematological parameters of male Wistar rats.
| Parameters | Dose (mg/kg body weight/day) | Control | 200 | 400 | 800 |
| White blood cell (×103/µL) | 7.77 ± 1.83 | 8.00 ± 0.98 | 6.87 ± 2.23 | 8.55 ± 2.47 | Red blood cell (×106/µL) | 8.45 ± 0.23 | 8.91 ± 0.41 | 8.69 ± 0.31 | 8.84 ± 0.54 | Haematocrit (%) | 0.46 ± 0.01 | 0.46 ± 0.02 | 0.47 ± 0.02 | 0.47 ± 0.02 | Haemoglobin (g/dL) | 15.83 ± 0.15 | 15.93 ± 0.64 | 16.10 ± 0.70 | 16.35 ± 0.64 | MCV (fL) | 54.67 ± 0.58 | 54.00 ± 0.00 | 54.33 ± 1.15 | 52.50 ± 0.71*** | MCH (pg) | 18.67 ± 0.58 | 18.00 ± 0.00 | 18.67 ± 0.58 | 18.30 ± 0.42 | MCHC (g/dL) | 34.67 ± 0.57 | 34.00 ± 0.00 | 34.00 ± 1.00 | 35.00 ± 0.0 | RDW (fL) | 19.20 ± 1.11 | 19.37 ± 0.49 | 19.77 ± 1.00 | 19.70 ± 1.56 | Neutrophils (%) | 1.76 ± 0.47 | 1.72 ± 0.65 | 1.69 ± 0.68 | 1.32 ± 0.25 | Lymphocytes (%) | 5.36 ± 1.36 | 5.72 ± 0.33 | 5.26 ± 1.47 | 6.55 ± 1.96* | Monocytes (%) | 0.32 ± 0.15 | 0.46 ± 0.11 | 0.37 ± 0.11 | 0.36 ± 0.08 | Eosinophils (%) | 0.13 ± 0.04 | 0.11 ± 0.07 | 0.16 ± 0.04 | 0.31 ± 0.13 | Basophils (%) |
0.01 ± 0.00 | 0.01 ± 0.00 |
0.01 ± 0.01 |
0.02 ± 0.00 | Platelets (×103/µL) | 914.67 ± 76.56 | 881.33 ± 70.63 | 872.00 ± 59.92 | 1006.50 ± 43.13*** |
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Values are presented as mean ± SEM (). *Statistically different from the control at . ***Statistically different from the control at .
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