Research Article

Berberine Reduces Neurotoxicity Related to Nonalcoholic Steatohepatitis in Rats

Table 2

Mean levels of serum oxidative stress and proinflammatory parameters in control, NASH, and berberine treated groups.

GroupsTBARS
nmol/mL
XO (µM/hour)GPx
(IU)
SOD (IU)GSH (mg/dL)TNF-alpha (pg/L)NO
(nmole/mL)

Control2.3 ± 0.213.4 ± 1.67.2 ± 0.53.4 ± 0.23.2 ± 0.387 ± 129.3 ± 3.1
Berberine control1.5 ± 0.112.1 ± 2.29.1 ± 0.54.1 ± 0.24 ± 0.176 ± 9.65 ± 0.9
NASH group10 ± 1.237.2 ± 5.24.2 ± 0.22.1 ± 0.11.4 ± 0.2500 ± 4530 ± 7.2
Berberine treatment5 ± 0.913.2 ± 4.26.1 ± 0.23.1 ± 0.53.2 ± 0.2150 ± 3010.3 ± 2.3

Values are reported as means ± SD of rat groups with different degrees of significance at .
Lowest value of significance.
Highest value of significance.
If two groups have the same letters, it means no significant difference is detected.