Research Article
Luteolin Exerts Cardioprotective Effects through Improving Sarcoplasmic Reticulum Ca2+-ATPase Activity in Rats during Ischemia/Reperfusion In Vivo
Figure 6
Luteolin improves SERCA2a activity through partially activating PI3K/Akt signaling pathway. The expression levels of p-Akt (308 and 473) and Akt (a and b), SERCA2a protein (c), and SERCA2a activity (d) of four groups which were subjected to ischemia for 30 min followed by reperfusion for 120 min were detected. The results are expressed as mean ± SD, . versus sham; , , and versus I/R; , versus group.
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