Antiosteoporosis Activity of New Oriental Medicine Preparation (Kyungokgo Mixed with Water Extract of Hovenia dulcis) on the Ovariectomized Mice
Effect of KOG, KOGHD10%, and KOGHD25% on trabecular morphometric parameters in proximal tibia and distal femur of OVX mice. Mice were treated with vehicle, HD (185 mg/kg/day, p.o) for 6 weeks. bone volume/tissue volume (BV/TV), bone surface/tissue volume (BS/TV), bone surface/Bone volume (BS/BV), structure model index (SMI), trabecular bone pattern factor (Tb.Pf), trabecular thickness (Tb.Th), trabecular number (Tb.N), and trabecular separation (Tb.Sp) as analyzed with micro-CT Skyscan CTAn software. Data are expressed as mean SD (). *, **, and *** versus OVX group (femur); #, ##, and ### versus SHAM group (femur); , , and versus OVX group (tibia); , , and versus SHAM group (tibia).