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Evidence-Based Complementary and Alternative Medicine
Volume 2015 (2015), Article ID 380615, 7 pages
http://dx.doi.org/10.1155/2015/380615
Review Article

Gray Matter Volumes in Patients with Chronic Fatigue Syndrome

1Acupuncture and Tuina School, The 3rd Teaching Hospital, Chengdu University of Traditional Chinese Medicine, No. 37 Shi’er Qiao Road, Chengdu, Sichuan 610075, China
2Institute for Social Medicine, Epidemiology and Health Economics, Charité University Medical Center, 10117 Berlin, Germany

Received 25 June 2014; Accepted 26 August 2014

Academic Editor: Cun-Zhi Liu

Copyright © 2015 Le-wei Tang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. C. H. Bombardier and D. Buchwald, “Chronic fatigue, chronic fatigue syndrome, and fibromyalgia,” Medical Care, vol. 34, no. 9, pp. 924–930, 1996. View at Publisher · View at Google Scholar · View at Scopus
  2. D. Buchwald, T. Pearlman, J. Umali, K. Schmaling, and W. Katon, “Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals,” The American Journal of Medicine, vol. 101, no. 4, pp. 364–370, 1996. View at Publisher · View at Google Scholar · View at Scopus
  3. Y. Watanabe, B. Evengard, B. H. Natelson, L. A. Jason, and H. Kuratsune, Fatigue Science for Human Health, Springer, 2008.
  4. L. Steele, J. G. Dobbins, K. Fukuda et al., “The epidemiology of chronic fatigue in San Francisco,” The American Journal of Medicine, vol. 105, supplement 1, no. 3, pp. 83S–90S, 1998. View at Publisher · View at Google Scholar · View at Scopus
  5. K. Fukuda, J. G. Dobbins, L. J. Wilson, R. A. Dunn, K. Wilcox, and D. Smallwood, “An epidemiologic study of fatigue with relevance for the chronic fatigue syndrome,” Journal of Psychiatric Research, vol. 31, no. 1, pp. 19–29, 1997. View at Publisher · View at Google Scholar · View at Scopus
  6. L. A. Jason, J. A. Richman, A. W. Rademaker et al., “A community-based study of chronic fatigue syndrome,” Archives of Internal Medicine, vol. 159, no. 18, pp. 2129–2137, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. Y. Christley, T. Duffy, and C. R. Martin, “A review of the definitional criteria for chronic fatigue syndrome,” Journal of Evaluation in Clinical Practice, vol. 18, no. 1, pp. 25–31, 2012. View at Publisher · View at Google Scholar · View at Scopus
  8. J. A. Richman, J. A. Flaherty, and K. M. Rospenda, “Chronic fatigue syndrome: have flawed assumptions been derived from treatment-based studies?” The American Journal of Public Health, vol. 84, no. 2, pp. 282–284, 1994. View at Publisher · View at Google Scholar · View at Scopus
  9. K. M. Jordan, D. A. Landis, M. C. Downey, S. L. Osterman, A. E. Thurm, and L. A. Jason, “Chronic fatigue syndrome in children and adolescents: a review,” Journal of Adolescent Health, vol. 22, no. 1, pp. 4–18, 1998. View at Publisher · View at Google Scholar · View at Scopus
  10. K. Fukuda, S. E. Straus, I. Hickie, M. C. Sharpe, J. G. Dobbins, and A. Komaroff, “The chronic fatigue syndrome: a comprehensive approach to its definition and study,” Annals of Internal Medicine, vol. 121, no. 12, pp. 953–959, 1994. View at Publisher · View at Google Scholar · View at Scopus
  11. J. B. Prins, G. Bleijenberg, E. Bazelmans et al., “Cognitive behaviour therapy for chronic fatigue syndrome: a multicentre randomised controlled trial,” The Lancet, vol. 357, no. 9259, pp. 841–847, 2001. View at Publisher · View at Google Scholar · View at Scopus
  12. R. Cairns and M. Hotopf, “A systematic review describing the prognosis of chronic fatigue syndrome,” Occupational Medicine, vol. 55, no. 1, pp. 20–31, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. L. Shulin, “The clinical observation of needling techniques to the combination on acupuncture with treat chronic fatigue syndrome,” Journal of Clinical Acupuncture and Moxibustion, vol. 7, pp. 14–16, 2012. View at Google Scholar
  14. L. Yali, Y. Guigui, and Y. Lijuan, “Therapeutic effect of acupuncture of back-shu points treating chronic fatigue syndrome and effect of psychological state,” Chinese Archives of Traditional Chinese Medicine, vol. 10, pp. 2327–2329, 2013. View at Google Scholar
  15. B. Biswal, P. Kunwar, and B. H. Natelson, “Cerebral blood flow is reduced in chronic fatigue syndrome as assessed by arterial spin labeling,” Journal of the Neurological Sciences, vol. 301, no. 1-2, pp. 9–11, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. K. Yoshiuchi, J. Farkas, and B. H. Natelson, “Patients with chronic fatigue syndrome have reduced absolute cortical blood flow,” Clinical Physiology and Functional Imaging, vol. 26, no. 2, pp. 83–86, 2006. View at Publisher · View at Google Scholar · View at Scopus
  17. K. B. Schmaling, “Single-photon emission computerized tomography and neurocognitive function in patients with chronic fatigue syndrome,” Psychosomatic Medicine, vol. 65, no. 1, pp. 129–136, 2003. View at Google Scholar
  18. D. H. Lewis, H. S. Mayberg, M. E. Fischer et al., “Monozygotic twins discordant for chronic fatigue syndrome: regional cerebral blood flow SPECT,” Radiology, vol. 219, no. 3, pp. 766–773, 2001. View at Publisher · View at Google Scholar · View at Scopus
  19. S. J. Mathew, X. Mao, K. A. Keegan et al., “Ventricular cerebrospinal fluid lactate is increased in chronic fatigue syndrome compared with generalized anxiety disorder: an in vivo 3.0 T 1H MRS imaging study,” NMR in Biomedicine, vol. 22, no. 3, pp. 251–258, 2009. View at Publisher · View at Google Scholar · View at Scopus
  20. W. K. Jerjes, N. F. Taylor, P. J. Wood, and A. J. Cleare, “Enhanced feedback sensitivity to prednisolone in chronic fatigue syndrome,” Psychoneuroendocrinology, vol. 32, no. 2, pp. 192–198, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. W. K. Jerjes, N. F. Taylor, T. J. Peters, S. Wessely, and A. J. Cleare, “Urinary cortisol and cortisol metabolite excretion in chronic fatigue syndrome,” Psychosomatic Medicine, vol. 68, no. 4, pp. 578–582, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. A. J. Cleare, “The HPA axis and the genesis of chronic fatigue syndrome,” Trends in Endocrinology & Metabolism, vol. 15, no. 2, pp. 55–59, 2004. View at Publisher · View at Google Scholar · View at Scopus
  23. R. Chen, J. Moriya, J.-I. Yamakawa et al., “Brain atrophy in a murine model of chronic fatigue syndrome and beneficial effect of Hochu-ekki-to (TJ-41),” Neurochemical Research, vol. 33, no. 9, pp. 1759–1767, 2008. View at Publisher · View at Google Scholar · View at Scopus
  24. S. W. Tang, E. Chu, T. Hui, D. Helmeste, and C. Law, “Influence of exercise on serum brain-derived neurotrophic factor concentrations in healthy human subjects,” Neuroscience Letters, vol. 431, no. 1, pp. 62–65, 2008. View at Publisher · View at Google Scholar · View at Scopus
  25. T. Katafuchi, T. Kondo, S. Take, and M. Yoshimura, “Brain cytokines and the 5-HT system during poly I:C-induced fatigue,” Annals of the New York Academy of Sciences, vol. 1088, pp. 230–237, 2006. View at Publisher · View at Google Scholar · View at Scopus
  26. A. J. Cleare, C. Messa, E. A. Rabiner, and P. M. Grasby, “Brain 5-HT1A receptor binding in chronic fatigue syndrome measured using positron emission tomography and [11C]WAY-100635,” Biological Psychiatry, vol. 57, no. 3, pp. 239–246, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. S. Yamamoto, Y. Ouchi, H. Onoe et al., “Reduction of serotonin transporters of patients with chronic fatigue syndrome,” NeuroReport, vol. 15, no. 17, pp. 2571–2574, 2004. View at Publisher · View at Google Scholar · View at Scopus
  28. W. Rostène, P. Kitabgi, and S. M. Parsadaniantz, “Chemokines: a new class of neuromodulator?” Nature Reviews Neuroscience, vol. 8, no. 11, pp. 895–903, 2007. View at Publisher · View at Google Scholar · View at Scopus
  29. B. H. Natelson, S. A. Weaver, C.-L. Tseng, and J. E. Ottenweller, “Spinal fluid abnormalities in patients with chronic fatigue syndrome,” Clinical and Diagnostic Laboratory Immunology, vol. 12, no. 1, pp. 52–55, 2005. View at Publisher · View at Google Scholar · View at Scopus
  30. G. Lange, J. Deluca, J. A. Maldjian, H.-J. Lee, L. A. Tiersky, and B. H. Natelson, “Brain MRI abnormalities exist in a subset of patients with chronic fatigue syndrome,” Journal of the Neurological Sciences, vol. 171, no. 1, pp. 3–7, 1999. View at Publisher · View at Google Scholar · View at Scopus
  31. G. Lange, A. I. Holodny, J. DeLuca et al., “Quantitative assessment of cerebral ventricular volumes in chronic fatigue syndrome,” Applied Neuropsychology, vol. 8, no. 1, pp. 23–30, 2001. View at Publisher · View at Google Scholar · View at Scopus
  32. H. Cope, A. Pernet, B. Kendall, and A. David, “Cognitive functioning and magnetic resonance imaging in chronic fatigue,” The British Journal of Psychiatry, vol. 167, pp. 86–94, 1995. View at Publisher · View at Google Scholar · View at Scopus
  33. H. Cope and A. S. David, “Neuroimaging in chronic fatigue syndrome,” Journal of Neurology Neurosurgery and Psychiatry, vol. 60, no. 5, pp. 471–473, 1996. View at Publisher · View at Google Scholar · View at Scopus
  34. T. Okada, M. Tanaka, H. Kuratsune, Y. Watanabe, and N. Sadato, “Mechanisms underlying fatigue: a voxel-based morphometric study of chronic fatigue syndrome,” BMC Neurology, vol. 4, no. 1, article 14, 2004. View at Publisher · View at Google Scholar · View at Scopus
  35. B. K. Puri, P. M. Jakeman, M. Agour et al., “Regional grey and white matter volumetric changes in myalgic encephalomyelitis (chronic fatigue syndrome): a voxel-based morphometry 3 T MRI study,” The British Journal of Radiology, vol. 85, no. 1015, pp. e270–e273, 2012. View at Publisher · View at Google Scholar · View at Scopus
  36. F. P. de Lange, J. S. Kalkman, G. Bleijenberg, P. Hagoort, J. W. M. van der Meer, and I. Toni, “Gray matter volume reduction in the chronic fatigue syndrome,” NeuroImage, vol. 26, no. 3, pp. 777–781, 2005. View at Publisher · View at Google Scholar · View at Scopus
  37. F. P. de Lange, A. Koers, J. S. Kalkman et al., “Increase in prefrontal cortical volume following cognitive behavioural therapy in patients with chronic fatigue syndrome,” Brain, vol. 131, part 8, pp. 2172–2180, 2008. View at Publisher · View at Google Scholar · View at Scopus
  38. X. Caseras, D. Mataix-Cols, K. A. Rimes et al., “The neural correlates of fatigue: an exploratory imaginal fatigue provocation study in chronic fatigue syndrome,” Psychological Medicine, vol. 38, no. 7, pp. 941–951, 2008. View at Publisher · View at Google Scholar · View at Scopus
  39. M. Tanaka, N. Sadato, T. Okada et al., “Reduced responsiveness is an essential feature of chronic fatigue syndrome: a fMRI study,” BMC Neurology, vol. 6, article 9, 2006. View at Publisher · View at Google Scholar · View at Scopus
  40. C. R. Rosenthal, E. E. Roche-Kelly, M. Husain, and C. Kennard, “Response-dependent contributions of human primary motor cortex and angular gyrus to manual and perceptual sequence learning,” Journal of Neuroscience, vol. 29, no. 48, pp. 15115–15125, 2009. View at Publisher · View at Google Scholar · View at Scopus
  41. C. Farrer, S. H. Frey, J. D. van Horn et al., “The angular gyrus computes action awareness representations,” Cerebral Cortex, vol. 18, no. 2, pp. 254–261, 2008. View at Publisher · View at Google Scholar · View at Scopus
  42. E. K. Miller and J. D. Cohen, “An integrative theory of prefrontal cortex function,” Annual Review of Neuroscience, vol. 24, pp. 167–202, 2001. View at Publisher · View at Google Scholar · View at Scopus
  43. L. R. Barnden, B. Crouch, R. Kwiatek et al., “A brain MRI study of chronic fatigue syndrome: evidence of brainstem dysfunction and altered homeostasis,” NMR in Biomedicine, vol. 24, no. 10, pp. 1302–1312, 2011. View at Publisher · View at Google Scholar · View at Scopus
  44. C. J. Woolf and M. W. Salter, “Neuronal plasticity: increasing the gain in pain,” Science, vol. 288, no. 5472, pp. 1765–1768, 2000. View at Publisher · View at Google Scholar · View at Scopus
  45. A. V. Apkarian, Y. Sosa, S. Sonty et al., “Chronic back pain is associated with decreased prefrontal and thalamic gray matter density,” Journal of Neuroscience, vol. 24, no. 46, pp. 10410–10415, 2004. View at Publisher · View at Google Scholar · View at Scopus
  46. N. Buckalew, M. W. Haut, L. Morrow, and D. Weiner, “Chronic pain is associated with brain volume loss in older adults: preliminary evidence,” Pain Medicine, vol. 9, no. 2, pp. 240–248, 2008. View at Publisher · View at Google Scholar · View at Scopus
  47. T. Schmidt-Wilcke, E. Leinisch, S. Gänßbauer et al., “Affective components and intensity of pain correlate with structural differences in gray matter in chronic back pain patients,” Pain, vol. 125, no. 1-2, pp. 89–97, 2006. View at Publisher · View at Google Scholar · View at Scopus
  48. T. Schmidt-Wilcke, E. Leinisch, A. Straube et al., “Gray matter decrease in patients with chronic tension type headache,” Neurology, vol. 65, no. 9, pp. 1483–1486, 2005. View at Publisher · View at Google Scholar · View at Scopus
  49. M. Burgmer, M. Gaubitz, C. Konrad et al., “Decreased gray matter volumes in the cingulo-frontal cortex and the amygdala in patients with fibromyalgia,” Psychosomatic Medicine, vol. 71, no. 5, pp. 566–573, 2009. View at Publisher · View at Google Scholar · View at Scopus
  50. M. C. Hsu, R. E. Harris, P. C. Sundgren et al., “No consistent difference in gray matter volume between individuals with fibromyalgia and age-matched healthy subjects when controlling for affective disorder,” Pain, vol. 143, no. 3, pp. 262–267, 2009. View at Publisher · View at Google Scholar · View at Scopus
  51. J. H. Kim, S.-I. Suh, H. Y. Seol et al., “Regional grey matter changes in patients with migraine: a voxel-based morphometry study,” Cephalalgia, vol. 28, no. 6, pp. 598–604, 2008. View at Publisher · View at Google Scholar · View at Scopus
  52. T. Schmidt-Wilcke, S. Gänßbauer, T. Neuner, U. Bogdahn, and A. May, “Subtle grey matter changes between migraine patients and healthy controls,” Cephalalgia, vol. 28, no. 1, pp. 1–4, 2008. View at Publisher · View at Google Scholar · View at Scopus
  53. W. Valfrè, I. Rainero, M. Bergui, and L. Pinessi, “Voxel-based morphometry reveals gray matter abnormalities in migraine,” Headache, vol. 48, no. 1, pp. 109–117, 2008. View at Publisher · View at Google Scholar · View at Scopus
  54. M. Valet, H. Gündel, T. Sprenger et al., “Patients with pain disorder show gray-matter loss in pain-processing structures: a voxel-based morphometric study,” Psychosomatic Medicine, vol. 71, no. 1, pp. 49–56, 2009. View at Publisher · View at Google Scholar · View at Scopus
  55. A. May, “Chronic pain may change the structure of the brain,” Pain, vol. 137, no. 1, pp. 7–15, 2008. View at Publisher · View at Google Scholar · View at Scopus
  56. R. Ruscheweyh, M. Deppe, H. Lohmann et al., “Pain is associated with regional grey matter reduction in the general population,” Pain, vol. 152, no. 4, pp. 904–911, 2011. View at Publisher · View at Google Scholar · View at Scopus
  57. S. E. Gwilym, N. Filippini, G. Douaud, A. J. Carr, and I. Tracey, “Thalamic atrophy associated with painful osteoarthritis of the hip is reversible after arthroplasty: a longitudinal voxel-based morphometric study,” Arthritis &Rheumatism, vol. 62, no. 10, pp. 2930–2940, 2010. View at Publisher · View at Google Scholar · View at Scopus
  58. R. Rodriguez-Raecke, A. Niemeier, K. Ihle, W. Ruether, and A. May, “Brain gray matter decrease in chronic pain is the consequence and not the cause of pain,” Journal of Neuroscience, vol. 29, no. 44, pp. 13746–13750, 2009. View at Publisher · View at Google Scholar · View at Scopus
  59. P. Y. Geha, M. N. Baliki, R. N. Harden, W. R. Bauer, T. B. Parrish, and A. V. Apkarian, “The brain in chronic CRPS pain: abnormal gray-white matter interactions in emotional and autonomic regions,” Neuron, vol. 60, no. 4, pp. 570–581, 2008. View at Publisher · View at Google Scholar · View at Scopus
  60. A. Kuchinad, P. Schweinhardt, D. A. Seminowicz, P. B. Wood, B. A. Chizh, and M. C. Bushnell, “Accelerated brain gray matter loss in fibromyalgia patients: premature aging of the brain?” Journal of Neuroscience, vol. 27, no. 15, pp. 4004–4007, 2007. View at Publisher · View at Google Scholar · View at Scopus
  61. T. Schmidt-Wilcke, R. Luerding, T. Weigand et al., “Striatal grey matter increase in patients suffering from fibromyalgia—a voxel-based morphometry study,” Pain, vol. 132, supplement 1, pp. S109–S116, 2007. View at Publisher · View at Google Scholar · View at Scopus
  62. C. R. Cloninger, “A unified biosocial theory of personality and its role in the development of anxiety states,” Psychiatric Developments, vol. 4, no. 3, pp. 167–226, 1986. View at Google Scholar · View at Scopus
  63. S. Gardini, C. R. Cloninger, and A. Venneri, “Individual differences in personality traits reflect structural variance in specific brain regions,” Brain Research Bulletin, vol. 79, no. 5, pp. 265–270, 2009. View at Publisher · View at Google Scholar · View at Scopus
  64. H. Yamasue, O. Abe, M. Suga et al., “Gender-common and -specific neuroanatomical basis of human anxiety-related personality traits,” Cerebral Cortex, vol. 18, no. 1, pp. 46–52, 2008. View at Publisher · View at Google Scholar · View at Scopus
  65. S. Hatcher and A. House, “Life events, difficulties and dilemmas in the onset of chronic fatigue syndrome: a case-control study,” Psychological Medicine, vol. 33, no. 7, pp. 1185–1192, 2003. View at Publisher · View at Google Scholar · View at Scopus
  66. E. Geuze, E. Vermetten, and J. D. Bremner, “MR-based in vivo hippocampal volumetrics: 1. Review of methodologies currently employed,” Molecular Psychiatry, vol. 10, no. 2, pp. 147–159, 2005. View at Publisher · View at Google Scholar · View at Scopus
  67. N. Kitayama, V. Vaccarino, M. Kutner, P. Weiss, and J. D. Bremner, “Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis,” Journal of Affective Disorders, vol. 88, no. 1, pp. 79–86, 2005. View at Publisher · View at Google Scholar · View at Scopus
  68. M. E. Smith, “Bilateral hippocampal volume reduction in adults with post-traumatic stress disorder: a meta-analysis of structural MRI studies,” Hippocampus, vol. 15, no. 6, pp. 798–807, 2005. View at Publisher · View at Google Scholar · View at Scopus
  69. B. Fischler, R. Cluydts, V. de Gucht, L. Kaufman, and K. de Meirleir, “Generalized anxiety disorder in chronic fatigue syndrome,” Acta Psychiatrica Scandinavica, vol. 95, no. 5, pp. 405–413, 1997. View at Publisher · View at Google Scholar · View at Scopus
  70. J. Angst and A. Dobler-Mikola, “The Zurich study. V. Anxiety and phobia in young adults,” European Archives of Psychiatry and Neurological Sciences, vol. 235, no. 3, pp. 171–178, 1985. View at Publisher · View at Google Scholar · View at Scopus
  71. S. Wessely, T. Chalder, S. Hirsch, P. Wallace, and D. Wright, “Psychological symptoms, somatic symptoms, and psychiatric disorder in chronic fatigue and chronic fatigue syndrome: a prospective study in the primary care setting,” The American Journal of Psychiatry, vol. 153, no. 8, pp. 1050–1059, 1996. View at Google Scholar · View at Scopus
  72. W. J. Katon, D. S. Buchwald, G. E. Simon, J. E. Russo, and P. J. Mease, “Psychiatric Illness in patients with chronic fatigue and those with rheumatoid arthritis,” Journal of General Internal Medicine, vol. 6, no. 4, pp. 277–285, 1991. View at Publisher · View at Google Scholar · View at Scopus
  73. G. C. Wood, R. P. Bentall, M. Gopfert, and R. H. T. Edwards, “A comparative psychiatric assessment of patients with chronic fatigue syndrome and muscle disease,” Psychological Medicine, vol. 21, no. 3, pp. 619–628, 1991. View at Publisher · View at Google Scholar · View at Scopus
  74. T. J. Lane, P. Manu, and D. A. Matthews, “Depression and somatization in the chronic fatigue syndrome,” The American Journal of Medicine, vol. 91, no. 4, pp. 335–344, 1991. View at Publisher · View at Google Scholar · View at Scopus
  75. S. Wessely and R. Powell, “Fatigue syndromes: a comparison of chronic ‘postviral' fatigue with neuromuscular and affective disorders,” Journal of Neurology Neurosurgery and Psychiatry, vol. 52, no. 8, pp. 940–948, 1989. View at Publisher · View at Google Scholar · View at Scopus
  76. P. Manu, D. A. Matthews, T. J. Lane et al., “Depression among patients with a chief complaint of chronic fatigue,” Journal of Affective Disorders, vol. 17, no. 2, pp. 165–172, 1989. View at Publisher · View at Google Scholar · View at Scopus
  77. D. W. Bates, W. Schmitt, D. Buchwald et al., “Prevalence of fatigue and chronic fatigue syndrome in a primary care practice,” Archives of Internal Medicine, vol. 153, no. 24, pp. 2759–2765, 1993. View at Publisher · View at Google Scholar · View at Scopus
  78. I. Hickie, A. Lloyd, D. Wakefield, and G. Parker, “The psychiatric status of patients with the chronic fatigue syndrome,” The British Journal of Psychiatry, vol. 156, pp. 534–540, 1990. View at Publisher · View at Google Scholar · View at Scopus
  79. M. Cella, P. D. White, M. Sharpe et al., “Cognitions, behaviours and co-morbid psychiatric diagnoses in patients with chronic fatigue syndrome,” Psychological Medicine, vol. 43, no. 2, pp. 375–380, 2013. View at Google Scholar
  80. R. Sprengelmeyer, J. D. Steele, B. Mwangi et al., “The insular cortex and the neuroanatomy of major depression,” Journal of Affective Disorders, vol. 133, no. 1-2, pp. 120–127, 2011. View at Publisher · View at Google Scholar · View at Scopus
  81. A. Silver, M. Haeney, P. Vijayadurai, D. Wilks, M. Pattrick, and C. J. Main, “The role of fear of physical movement and activity in chronic fatigue syndrome,” Journal of Psychosomatic Research, vol. 52, no. 6, pp. 485–493, 2002. View at Publisher · View at Google Scholar · View at Scopus
  82. S. P. van der Werf, J. B. Prins, J. H. M. M. Vercoulen, J. W. M. van der Meer, and G. Bleijenberg, “Identifying physical activity patterns in chronic fatigue syndrome using actigraphic assessment,” Journal of Psychosomatic Research, vol. 49, no. 5, pp. 373–379, 2000. View at Publisher · View at Google Scholar · View at Scopus
  83. S. Colcombe and A. F. Kramer, “Fitness effects on the cognitive function of older adults: a meta-analytic study,” Psychological Science, vol. 14, no. 2, pp. 125–130, 2003. View at Publisher · View at Google Scholar · View at Scopus
  84. S. J. Colcombe, K. I. Erickson, P. E. Scalf et al., “Aerobic exercise training increases brain volume in aging humans,” Journals of Gerontology A: Biological Sciences and Medical Sciences, vol. 61, no. 11, pp. 1166–1170, 2006. View at Publisher · View at Google Scholar · View at Scopus
  85. E. Altena, H. Vrenken, Y. D. van der Werf, O. A. van den Heuvel, and E. J. W. van Someren, “Reduced orbitofrontal and parietal gray matter in chronic insomnia: a voxel-based morphometric study,” Biological Psychiatry, vol. 67, no. 2, pp. 182–185, 2010. View at Publisher · View at Google Scholar · View at Scopus
  86. N. Afari and D. Buchwald, “Chronic fatigue syndrome: a review,” The American Journal of Psychiatry, vol. 160, no. 2, pp. 221–236, 2003. View at Publisher · View at Google Scholar · View at Scopus