Farnesol, a Sesquiterpene Alcohol in Herbal Plants, Exerts Anti-Inflammatory and Antiallergic Effects on Ovalbumin-Sensitized and -Challenged Asthmatic Mice

Table 3

Effects of farnesol supplementation with different doses for 5 weeks on absolute and relative weights of visceral organs of OVA/AL-sensitized and -challenged BALB/c asthmatic mice.

Organ	Group	DC	FL	FM	FH	PC	NSC
		13	14	12	14	14	15
Spleen	ATW (g)	0.15 ± 0.03^a	0.14 ± 0.01^a	0.14 ± 0.02^a	0.14 ± 0.03^a	0.12 ± 0.01^b	0.15 ± 0.03^a
	RTW (%)	0.76 ± 0.16^a	0.64 ± 0.21^ab	0.68 ± 0.11^ab	0.70 ± 0.15^ab	0.58 ± 0.38^b	0.72 ± 0.11^a
Liver	ATW (g)	1.29 ± 0.11	1.33 ± 0.11	1.29 ± 0.13	1.29 ± 0.17	1.31 ± 0.11	1.36 ± 0.21
	RTW (%)	6.56 ± 0.32	6.51 ± 0.28	6.31 ± 0.51	6.25 ± 0.61	6.67 ± 0.08	6.61 ± 0.68
Kidney	ATW (g)	0.30 ± 0.03	0.30 ± 0.06	0.32 ± 0.02	0.31 ± 0.03	0.30 ± 0.02	0.30 ± 0.04
	RTW (%)	1.53 ± 0.12	1.44 ± 0.20	1.42 ± 0.46	1.52 ± 0.10	1.54 ± 0.05	1.49 ± 0.18
Heart	ATW (g)	0.12 ± 0.02	0.12 ± 0.01	0.12 ± 0.01	0.12 ± 0.01	0.12 ± 0.01	0.12 ± 0.01
	RTW (%)	0.61 ± 0.07	0.58 ± 0.06	0.61 ± 0.04	0.57 ± 0.18	0.61 ± 0.01	0.58 ± 0.03
Thymus	ATW (g)	0.02 ± 0.01^a	0.02 ± 0.01^a	0.02 ± 0.01^a	0.02 ± 0.00^a	0.01 ± 0.00^b	0.03 ± 0.01^a
	RTW (%)	0.11 ± 0.03^a	0.12 ± 0.04^a	0.11 ± 0.03^a	0.12 ± 0.02^a	0.04 ± 0.16^b	0.13 ± 0.04^a
Epididymal fat	ATW (g)	0.34 ± 0.13^b	0.40 ± 0.08^ab	0.40 ± 0.09^ab	0.40 ± 0.12^ab	0.47 ± 0.12^a	0.42 ± 0.16^ab
	RTW (%)	1.71 ± 0.60^b	1.70 ± 0.79^b	1.95 ± 0.41^ab	1.94 ± 0.57^ab	2.38 ± 0.06^a	2.02 ± 0.78^ab

Values are means ± SD ( = 12–15). Values within same row not sharing a common small letter are significantly different () from each other and assayed by one-way ANOVA, followed by Duncan’s new multiple range test. NSC, nonsensitized control; DC, dietary control; PC, positive control; FL, low dose farnesol (0.003% in AIN-76 feed); FM, medium dose farnesol (0.017% in AIN-76 feed); FH, high dose farnesol (0.067% in AIN-76 feed); ATW, absolute tissue weight; RTW, relative tissue weight.