Research Article

Electroacupuncture Suppressed Neuronal Apoptosis and Improved Cognitive Impairment in the AD Model Rats Possibly via Downregulation of Notch Signaling Pathway

Figure 1

EA restored learning and memory in Aβ1–40-infused rat model. (a) Representative navigation traces of each group performing the Morris water maze task on day 5. (b) Escape latencies per day as assessed by the Morris water maze task. Improvement of cognitive function was only observed in the EA group and not in the sham-EA group. (c) Swimming speed was not significantly different among groups. (d) Probe analysis was performed on day 6. EA treated rats performed significantly better than the model and sham-EA treated rats based on the number of platform location crosses. (e) Rats received EA treatment remained in the original platform quadrant longer compared to model and sham-EA treated rats. and versus control, and versus model, and and versus sham-EA.
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