Is Huachansu Beneficial in Treating Advanced Non-Small-Cell Lung Cancer? Evidence from a Meta-Analysis of Its Efficacy Combined with Chemotherapy

Table 1

Characteristics of the included studies.

Study	Year	Stage of disease	Sample size (case/control)	Sex (F/M)	Age (median or mean or range)	Intervention		Treatment duration (week)	Description of random allocation method
						Test group	Control group
Bao et al. [10]	2011	III, IV	45/48	N	56/52 (T/C)	Huachansu + GP	GP	6	N
Cao [11]	2009	III, IV	25/25	22/28	58	Huachansu + GP	GP	9	N
Ding [12]	2011	III, IV	39/39	14/64	53	Huachansu + NI	NI	6	N
Dong [13]	2013	IV	46/40	39/47	46~66/48~69 (T/C)	Huachansu + pemetrexed + DDP	Pemetrexed + DDP	12	Random number table
Hu [14]	2012	III, IV	36/38	31/43	36~66	Huachansu + TP	TP	12~18	N
Jing [15]	2007	III, IV	32/28	18/42	65/65 (T/C)	Huachansu + NC	NC	8	By the order of admission
Li [16]	2011	III, IV	21/18	14/25	57.5/61 (T/C)	Huachansu + DC	DC	9~12	N
Li et al. [17]	2007	III, IV	32/32	11/53	56.3	Huachansu + NP/GP	NP/GP	2	N
Li et al. [18]	2010	III, IV	30/30	22/38	54	Huachansu + NP/EP	NP/EP	6	N
Liu [19]	2014	III, IV	45/40	38/47	47.5 ± 11.33	Huachansu + NP/TP	NP/TP	6	Random number table
Miao et al. [20]	2007	III, IV	43/44	37/50	54 ± 20/53 ± 19 (T/C)	Huachansu + NP	NP	9~18	Envelope randomization
Miao et al. [21]	2014	III, IV	30/30	29/31	58.0 ± 7.0/57.0 ± 6.5 (T/C)	Huachansu + TP	TP	12	Random number table
Qi [22]	2011	III, IV	30/30	12/48	53	Huachansu + TP/GP/NP	TP/GP/NP	6	N
Wang [23]	2006	III, IV	30/30	18/42	58.8/60.2 (T/C)	Huachansu + TP	TP	4	N
Xiong and Li [24]	2005	III, IV	32/30	20/42	49.7	Huachansu + NP	NP	8	By the order of admission
Yang and Xi [25]	2006	III, IV	30/30	22/38	52	Huachansu + NP	NP	6	N
Yu et al. [26]	2012	III, IV	32/32	25/39	64/62 (T/C)	Huachansu + DC	DC	4	N

N: not mentioned; F: female; M: male; DDP = cisplatin; NP = vinorelbine + cisplatin; NC = vinorelbine + carboplatin; TP = paclitaxel + cisplatin; DC = docetaxel + cisplatin; GP = gemcitabine + cisplatin; EP = etoposide + cisplatin; NI = vinorelbine + ifosfamide; T/C: test group/control group.