Sulforaphane Reverses the Expression of Various Tumor Suppressor Genes by Targeting DNMT3B and HDAC1 in Human Cervical Cancer Cells

Figure 4

Predicted interaction between ligands (SFN and 5-Aza-dC) with mDNMT3B. The mDNMT3B is depicted in ribbon representation showing docked models of SFN in red and 5-Aza-dC in blue and the residues defining the pocket as light blue. Inset focuses on the binding pocket shown in orange. Active site C-651 and cofactor binding E-605 are labeled and shown in purple solid bonds.