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Evidence-Based Complementary and Alternative Medicine
Volume 2015 (2015), Article ID 413075, 7 pages
Research Article

IQP-VV-102, a Novel Proprietary Composition for Weight Reduction: A Double-Blind Randomized Clinical Trial for Evaluation of Efficacy and Safety

1Practice for General Medicine, Kurfürstendamm 157/158, 10709 Berlin, Germany
2Analyze & Realize GmbH, Weißenseer Weg 111, 10369 Berlin, Germany
3Analyze & Realize GmbH, Waldseeweg 6, 13467 Berlin, Germany

Received 24 December 2014; Accepted 16 March 2015

Academic Editor: Raffaele Capasso

Copyright © 2015 Barbara Grube et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The individual ingredients in IQP-VV-102 have demonstrated promising effects in reducing sugar and starch digestion, which potentially leads to weight loss. The trial objective was to evaluate the safety and efficacy of IQP-VV-102 in reducing body weight in overweight and obese subjects. 120 overweight and obese individuals aged 18 to 60 years were randomly assigned to 2 treatment arms (IQP-VV-102 and placebo). The trial was conducted in 2 study centres in Berlin, Germany. The primary efficacy analysis was conducted on 117 subjects (IQP-VV-102: ; placebo: ), comparing the weight loss effect at baseline and 12 weeks after randomization. There was a statistically significant reduction in mean body weight of 3.29 kg (SD 2.30) in the IQP-VV-102 group compared to 0.83 kg (SD 2.00) in the placebo group . There were no serious or product-related adverse events that were reported over the combined period of 14 weeks. The findings suggested that IQP-VV-102 is effective and safe in body weight reduction in overweight and obese individuals in the short term. The study is registered under as NCT01681069.