Extract of Allium tuberosum Rottler ex Spreng Promoted the Hair Growth through Regulating the Expression of IGF-1

Figure 3

The n-butanol extract of ATRES showed the highest level of hair growth promoting activity. The insoluble fraction of the ethanol extract was first used for the subsequent extraction with different solvents. (a) The hair growth promoting activity was photographed at 10 days ((A), (B), (C), (D), and (E)) and 14 days ((F), (G), (H), (I), and (J)) after treatment and compared with the mouse groups that were administrated ethanol ((B), (G)), n-butanol ((C), (H)), n-hexane ((D), (I)), and DW ((E), (J)) extracts (3% in 150 uL volume of 40% ethanol). (b) Anagenic areas (complete black area) at 14 days of treatment were calculated using the Image J program and the n-butanol extract treated group showed the most enhanced hair growth. Data are presented as the means ± SD () and different letters of (b) indicate significant differences () between the groups.

(a)

(b)