Suppression of Propionibacterium acnes-Induced Dermatitis by a Traditional Japanese Medicine, Jumihaidokuto, Modifying Macrophage Functions

Figure 3

HE staining of pinna 24 h after P. acnes injection. The pinnae were excised at 24 h after the P. acnes injection and evaluated histologically by hematoxylin and eosin (HE) staining. Representative images of low-power (upper panels) and high-power (middle and lower panels) fields in pinna sections are shown for saline + DW ((a), (b), and (c)), P. acnes + DW ((d), (e), and (f)), P. acnes + 0.5 g/kg jumihaidokuto (JHT) ((g), (h), and (i)), and P. acnes + 10 mg/kg prednisolone (PDN) ((j), (k), and (l)). Yellow boxes indicate the sites of each magnification, and arrows indicate macrophage-like cells. Scale bars: 100 μm.