Research Article

Antiulcerogenic Activity and Toxicity of Bauhinia holophylla Hydroalcoholic Extract

Table 3

Effect of Bauhinia holophylla (150 mg/kg) on ethanol-induced gastric ulcer area (mm2) in rats that were pretreated with L-NAME (NO synthase inhibitor) or NEM (SH compound blocker).

Pretreatment (i.p.)Treatment (p.o.)Ulcer area (mm2)Gastroprotection (%)

VehicleVehicle643.71 ± 113.76
B. holophylla 220.42 ± 68.6765.75

L-NAME 70 mg/kgVehicle617.74 ± 116.73
B. holophylla 419.24 ± 131.3232.13

NEM 5 mg/kgVehicle460.38 ± 136.06
B. holophylla 608.93 ± 215.24

The results are reported as the mean ± SEM. Unpaired -test, .