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Evidence-Based Complementary and Alternative Medicine
Volume 2015, Article ID 472876, 10 pages
http://dx.doi.org/10.1155/2015/472876
Research Article

The Anti-Porcine Parvovirus Activity of Nanometer Propolis Flavone and Propolis Flavone In Vitro and In Vivo

1Medicinal Engineering Department of Henan University of Animal Husbandry and Economy, Zhengzhou, Henan 450011, China
2Binzhou Animal Science & Veterinary Medicine Academy of Shandong Province, Binzhou, Shandong 256600, China
3College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi 712100, China

Received 16 December 2014; Revised 9 February 2015; Accepted 11 February 2015

Academic Editor: Jae Youl Cho

Copyright © 2015 Xia Ma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. X. F. Kong, Y. L. Hu, R. Rui, D. Y. Wang, and X. R. Li, “Effects of Chinese herbal medicinal ingredients on peripheral lymphocyte proliferation and serum antibody titer after vaccination in chicken,” International Immunopharmacology, vol. 4, no. 7, pp. 975–982, 2004. View at Publisher · View at Google Scholar · View at Scopus
  2. W. L. Mengeling, “Porcine parvovirus,” in Diseases of Swine, B. E. Straw, J. J. Zimmerman, S. D'Allaire, and D. J. Taylor, Eds., Blackwell, Ames, Iowa, USA, 9th edition, 2006. View at Google Scholar
  3. R. Drolet, S. D'Allaire, R. Larochelle, R. Magar, M. Ribotta, and R. Higgins, “Infectious agents identified in pigs with multifocal interstitial nephritis at slaughter,” Veterinary Record, vol. 150, no. 5, pp. 139–143, 2002. View at Publisher · View at Google Scholar · View at Scopus
  4. K. M. Lager and W. L. Mengeling, “Porcine parvovirus associated with cutaneous lesions in piglets,” Journal of Veterinary Diagnostic Investigation, vol. 6, no. 3, pp. 357–359, 1994. View at Publisher · View at Google Scholar · View at Scopus
  5. J. Segalés, G. M. Allan, and M. Domingo, “Porcine circovirus diseases,” Animal Health Research Reviews, vol. 6, no. 2, pp. 119–142, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. Y. B. Ji, Chemistry and Pharmacology of Chinese Herbal Medicine Compound, People's Health Press, Beijing, China, 2003.
  7. P. Schnitzler, A. Schuhmacher, A. Astani, and J. Reichling, “Melissa officinalis oil affects infectivity of enveloped herpesviruses,” Phytomedicine, vol. 15, no. 9, pp. 734–740, 2008. View at Publisher · View at Google Scholar · View at Scopus
  8. Q. W. Zhang and C. Y. Zhang, “The latest research progress of the traditional Chinese medicine on antiviral,” Traditional Chinese Patent Medicine, vol. 1, pp. 116–119, 2005. View at Google Scholar
  9. Y. Fan, L. Ma, W. Zhang et al., “Microemulsion can improve the immune-enhancing activity of propolis flavonoid on immunosuppression and immune response,” International Journal of Biological Macromolecules, vol. 63, pp. 126–132, 2014. View at Publisher · View at Google Scholar · View at Scopus
  10. Y. P. Fan, Y. L. Hu, D. Y. Wang et al., “Epimedium polysaccharide and propolis flavone can synergistically stimulate lymphocyte proliferation in vitro and enhance the immune responses to ND vaccine in chickens,” International Journal of Biological Macromolecules, vol. 47, no. 2, pp. 87–92, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. Z. Yuqing, S. Zhan'ao, L. Jiaguo et al., “Flavone ingredients can synergistically inhibit NDV infecting cell and improve ND vaccine's protective rate,” International Journal of Biological Macromolecules, vol. 51, no. 3, pp. 201–208, 2012. View at Publisher · View at Google Scholar · View at Scopus
  12. X. Ma, Z. H. Guo, Z. Q. Shen, J. L. Wang, Y. L. Hu, and D. Y. Wang, “The immune enhancement of propolis adjuvant on inactivated porcine parvovirus vaccine in guinea pig,” Cellular Immunology, vol. 270, no. 1, pp. 13–18, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. J. Q. Chai, L. Wang, X. Pang, and Z. Q. Shen, “Influences of namometer propolis pellets on the immune function of chicken,” Acta Veterinaria et Zootechnica Sinica, vol. 33, pp. 412–416, 2002. View at Google Scholar
  14. X. Y. Huang, D. Y. Wang, Y. L. Hu et al., “Effect of sulfated astragalus polysaccharide on cellular infectivity of infectious bursal disease virus,” International Journal of Biological Macromolecules, vol. 42, no. 2, pp. 166–171, 2008. View at Publisher · View at Google Scholar · View at Scopus
  15. P. Rao, H. G. Wu, Y. H. Jiang et al., “Development of an EvaGreen-based multiplex real-time PCR assay with melting curve analysis for simultaneous detection and differentiation of six viral pathogens of porcine reproductive and respiratory disorder,” Journal of Virological Methods, vol. 208, pp. 56–62, 2014. View at Publisher · View at Google Scholar
  16. Y. L. Hu, X. F. Kong, X. R. Li, D. Y. Wang, J. G. Liu, and B. K. Zhang, “Effects of ten Chinese herbal medicinal ingredients on proliferation and resisting NDV infection of CEF,” Acta Veterinaria et Zootechnica Sinica, vol. 35, pp. 301–305, 2004. View at Google Scholar
  17. F. Delie, “Evaluation of nano- and microparticle uptake by the gastrointestinal tract,” Advanced Drug Delivery Reviews, vol. 34, no. 2-3, pp. 221–233, 1998. View at Publisher · View at Google Scholar · View at Scopus
  18. C. Caruso, E. Gobbi, T. Biosa, M. Andra, U. Cavallazzi, and L. Masoero, “Evaluation of viral inactivation of pseudorabies virus, encephalomyocarditis virus, bovine viral diarrhea virus and porcine parvovirus in pancreatin of porcine origin,” Journal of Virological Methods, vol. 208, pp. 79–84, 2014. View at Publisher · View at Google Scholar
  19. H. S. Joo, T. W. Molitor, and A. D. Leman, “Antibody responses of guinea-pigs, rabbits and pigs to inactivated porcine parvovirus vaccines,” Veterinary Microbiology, vol. 9, no. 1, pp. 27–33, 1984. View at Publisher · View at Google Scholar · View at Scopus
  20. Y. P. Fan, L. Ma, W. M. Zhang et al., “The design of propolis flavone microemulsion and its effect on enhancing the immunity and antioxidant activity in mice,” International Journal of Biological Macromolecules, vol. 65, pp. 200–207, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Herr, H. Bostedt, and K. Failing, “IgG and IgM levels in dairy cows during the periparturient period,” Theriogenology, vol. 75, no. 2, pp. 377–385, 2011. View at Publisher · View at Google Scholar · View at Scopus
  22. H. C. Yang, Animal Immunology, Chinese Agricultural University Press, Beijing, China, 2003.
  23. N. X. Nhiem, P. V. Kiem, C. V. Minh et al., “Structure-activity relationship of lupane-triterpene glycosides from Acanthopanax koreanum on spleen lymphocyte IL-2 and IFN-γ,” Bioorganic and Medicinal Chemistry Letters, vol. 20, no. 16, pp. 4927–4931, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. G. Fischer, F. R. Conceição, F. P. L. Leite et al., “Immunomodulation produced by a green propolis extract on humoral and cellular responses of mice immunized with SuHV-1,” Vaccine, vol. 25, no. 7, pp. 1250–1256, 2007. View at Publisher · View at Google Scholar · View at Scopus
  25. D. C. Merz, A. Scheid, and P. W. Choppin, “Immunological studies of the functions of paramyxovirus glycoproteins,” Virology, vol. 109, no. 1, pp. 94–105, 1981. View at Publisher · View at Google Scholar · View at Scopus
  26. J. M. Sforcin, R. O. Orsi, and V. Bankova, “Effect of propolis, some isolated compounds and its source plant on antibody production,” Journal of Ethnopharmacology, vol. 98, no. 3, pp. 301–305, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. Z. H. Guo, Y. L. Hu, D. Y. Wang et al., “Sulfated modification can enhance the adjuvanticity of lentinan and improve the immune effect of ND vaccine,” Vaccine, vol. 27, no. 5, pp. 660–665, 2009. View at Publisher · View at Google Scholar · View at Scopus