Research Article

The Mechanism Research of Qishen Yiqi Formula by Module-Network Analysis

Table 5

GO biological process terms of the modules of QSYQ.

Modules valueGO terms

11.97E − 14Regulation of protein metabolic process
21.32E − 32DNA metabolic process
32.01E − 28Regulation of cAMP metabolic process
44.16E − 24G-protein coupled receptor signaling pathway
55.28E − 23DNA-dependent transcription, initiation
63.03E − 25Transmembrane receptor protein tyrosine kinase signaling pathway
74.74E − 23Cellular lipid metabolic process
86.43E − 15Apoptotic process
91.80E − 18Tricarboxylic acid cycle
109.96E − 27G-protein coupled receptor signaling pathway
111.32E − 32Xenobiotic metabolic process
122.74E − 15Toll-like receptor signaling pathway
135.96E − 32Potassium ion transport
141.50E − 20Lipid metabolic process
152.57E − 20Xenobiotic metabolic process
168.66E − 12Positive regulation of RNA metabolic process
172.78E − 27Regulation of blood coagulation
183.33E − 14Inflammatory response
191.94E − 16Immune response-activating signal transduction
203.65E − 19Apoptotic process
211.04E − 11Regulation of blood coagulation
222.64E − 16Nucleotide metabolic process
234.14E − 13Transmembrane receptor protein tyrosine kinase signaling pathway
243.85E − 12Interferon-gamma-mediated signaling pathway
255.59E − 07Regulation of cellular protein metabolic process
264.34E − 06RNA processing
271.19E − 22Cell cycle phase transition
282.71E − 06Regulation of RNA metabolic process
299.03E − 14Regulation of systemic arterial blood pressure by renin-angiotensin
305.05E − 18Cardiac muscle contraction
312.53E − 06Regulation of RNA splicing
321.13E − 09Carbohydrate metabolic process
339.21E − 14Insulin receptor signaling pathway
343.77E − 08Lipid catabolic process
352.50E − 22Cellular amino acid catabolic process
361.93E − 17Regulation of cell cycle
372.42E − 14Lipid metabolic process
383.52E − 17mRNA metabolic process
392.31E − 06Execution phase of apoptosis
401.16E − 15Toll-like receptor signaling pathway
413.70E − 11RNA biosynthetic process
423.65E − 12Cell cycle phase
432.80E − 12Cellular amino acid metabolic process
446.84E − 05Regulation of cell proliferation
451.17E − 07Inflammatory response
464.51E − 09RNA biosynthetic process
473.74E − 11Regulation of interleukin-1 secretion
481.49E − 13DNA repair
491.67E − 18Insulin receptor signaling pathway
503.18E − 06Negative regulation of RNA metabolic process
511.24E − 04Transport
528.34E − 14Regulation of transforming growth factor beta receptor signaling pathway
534.47E − 06Xenobiotic metabolic process
541.16E − 08Negative regulation of inflammatory response
551.37E − 07Positive regulation of RNA metabolic process
565.56E − 07Transmission of nerve impulse
575.79E − 12Mitotic cell cycle
586.69E − 06Negative regulation of protein metabolic process
592.66E − 12Regulation of apoptotic signaling pathway
602.00E − 09Regulation of apoptotic signaling pathway
612.47E − 11NIK/NF-kappaB cascade
624.69E − 15Vascular endothelial growth factor receptor signaling pathway
631.98E − 06DNA metabolic process
642.04E − 04Chromatin organization
651.11E − 05DNA packaging
669.39E − 07Inflammatory response
673.22E − 09Xenobiotic metabolic process
688.09E − 12Insulin receptor signaling pathway
698.52E − 04DNA-dependent transcription, initiation
701.56E − 05DNA replication
715.51E − 07Toll-like receptor signaling pathway
722.16E − 08Copper ion import
732.90E − 08Transmission of nerve impulse
744.63E − 07Regulation of blood coagulation
766.90E − 04Alanine catabolic process
776.76E − 05RNA biosynthetic process
787.60E − 04Lipid metabolic process
792.86E − 05TRIF-dependent toll-like receptor signaling pathway
814.18E − 05Regulation of type I interferon production
835.21E − 03Cellular lipid metabolic process
841.27E − 11Neural crest cell migration
852.10E − 03AMP catabolic process

Notes. value is the probability of obtaining the observed effect under the null hypothesis; a very small value indicates that the observed effect is very unlikely to have arisen purely by chance.