In Vitro Pharmacological Activities and GC-MS Analysis of Different Solvent Extracts of Lantana camara Leaves Collected from Tropical Region of Malaysia
Table 4
Antibacterial activity of different solvent extracts of L. camara at different concentrations.
Solvent extracts (µL/disc)
Zone of inhibition (mm)
Escherichia coli
Klebsiella pneumoniae
Micrococcus luteus
Bacillus subtilis
Staphylococcus aureus
Ethyl acetate
2.5
08.2 ± 0.8
06.9 ± 0.5
06.1 ± 0.7
10.0 ± 0.5
—
5.0
13.0 ± 0.9
08.3 ± 0.5
07.1 ± 0.3
13.8 ± 0.5
06.1 ± 0.1
10.0
12.0 ± 0.5
10.5 ± 0.8
07.0 ± 0.5
13.9 ± 0.4
10.6 ± 0.4
Methanol
2.5
14.6 ± 0.5
08.2 ± 0.3
08.1 ± 0.7
10.0 ± 0.3
14.1 ± 0.2
5.0
18.2 ± 0.2
14.5 ± 0.5
12.2 ± 0.3
14.0 ± 0.6
16.1 ± 0.6
10.0
24.1 ± 0.4
18.1 ± 0.4
18.0 ± 0.5
16.1 ± 0.2
18.0 ± 0.4
Acetone
2.5
16.1 ± 0.4
06.1 ± 0.6
07.9 ± 0.2
14.2 ± 0.3
05.8 ± 0.6
5.0
24.0 ± 0.4
10.1 ± 0.6
12.3 ± 0.2
15.9 ± 0.4
10.2 ± 0.2
10.0
28.2 ± 0.6
16.2 ± 0.2
12.2 ± 0.2
16.3 ± 0.4
12.2 ± 0.4
Chloroform
2.5
10.6 ± 0.6
—
—
10.5 ± 0.9
—
5.0
12.9 ± 0.6
09.2 ± 0.2
06.8 ± 0.7
12.1 ± 0.7
07.2 ± 0.2
10.0
14.8 ± 0.3
11.4 ± 0.8
08.2 ± 0.2
12.4 ± 0.4
07.9 ± 0.2
Note: the negative control discs were soaked with 50 μL DMSO and the positive control discs with 50 μL (50 μg/mL) chloramphenicol. Each value represents the mean ± standard deviation (SD) of 3 replicates per treatment in 3 repeated experiments. “—” represents no activity.
